This article presents the most important issues concerning the medical aspects of anti-epidemic measures for brucellosis at the present stage. The system of epidemiological protection of the population provides early detection of infectious disease and informing the sanitary-epidemiological service, preventive, curative and rehabilitative measures. For example, in the Saratov region discusses the quality and volume of laboratory tests for brucellosis, the awareness of doctors about this infectious disease, state statistical reporting. Obtained evidence of signifi cant defi ciencies in the health care anti-epidemic measures for brucellosis associated with inadequate use of modern methods of laboratory diagnosis, incomplete volume survey of groups at high risk of infection with Brucella, decreased alertness and low level of awareness among physicians regarding brucellosis.