Сравнительная Оценка Специфичности И Чувствительности Иммунохроматографического Экспресс\теста И Полимеразной Цепной Реакции При Верификации Тяжелых Форм Пневмококковых Пневмоний

Comparative efficacy of the polymerase chain reaction (PCR) and the immunochromatographic method (ICM) in the etiolo! gical decoding of severe pneumococcal pneumonia is lacking, which hinders the optimal choice of the method of laboratory diagnosis for practitioners. The aim of the study – the comparative evaluation of the specificity and sensitivity of PCR and ICM in severe pneumococcal pneumonia verification. Methods of investigation. Еvaluation of PCR and ICM sensitivity and specificity was conducted on the basis of Perm regio! nal clinical infectious diseases hospital in 2012-2015, when 32 patients with severe community!acquired pneumonia were exa! mined. As a «gold standard» bacteriological method was used. Results. In diagnosis of pneumococcal pneumonia using ICM high sensitivity – 84,2 % and specificity – 92,3 % was set. PCR’s sensitivity was 73,6 %, specificity – 69,2 %. Scope. Practical health. Conclusion. The study on diagnostic value of two laboratory tests used in severe pneumococcal pneumonia verification sho! wed clear advantages of ICM with respect to PCR.