Photodynamic therapy is a promising method for the treatment of tumors with a broad potential of clinical and research applications. The possibility to combine the diagnostic and therapeutic options is of particular note that can significantly improve treatment efficiency. However, it is important to consider carefully the issues of service organization for the photodynamic therapy. Specialists’ inadequate education, incomplete service ensuring with medical and diagnostic equipment and non-compliance of treatment protocols can lead to a significant deterioration in the results and discredit the method.