The commentary tradition evolved worldwide due to the complexity of primary texts in different fields, including Ayurveda. The prime text, such as Aṣṭāṅgahṛdaya (AH), has nearly 44 commentaries written by the great commentators Candranandana, Aruṇadatta, Indu, Śrīdāsapaṇḍita, and others. Among AH's commentaries, Hṛdayabodhikā (HB) was comprehensive even for readers with varying levels of textual training and incorporated the opinions of other commentators. This study focuses on a brief overview of HB commentary on AH. The objectives of this study are to gather preliminary information about the HB commentary, including its title, authorship, period, narrative style, and content. HB has two more title names, such as Hṛdayabodhini and Aṣṭāṅgahṛdayadīpikā. The author is Śrīdāsapaṇḍita; the period dates from the latter half of the thirteenth century to the first half of the fourteenth century. The Malayalam terms influenced by Tamil found in the HB support the historical origin of Malayalam from Tamil. The study concludes that HB contains rich content, including different citations, similes, and practical explanations. Altogether, the study of HB commentary can contribute to the history of ancient medicine in India and other historical research perspectives, such as the history of language, medicine, and others.