In the present survey, the effect of application of two rotary cylinders on the MHD mixed-convection of a water-graphene nanofluid into a wavy cavity is investigated numerically. The two vertical walls of cavity are adiabatic whereas the bottom and top wavy walls are assumed to be the hot and cold ones with temperatures of T h and T c , respectively. The rotary cylinders are considered to be adiabatic. The finite volume numerical manner is put to use to simulate the mixed-convection flow inside the cavity. The impacts of rotational velocity and rotation direction of cylinders at Gr = 10 6 , 10 7 , and 10 8 are examined. The results have shown that by the contribution of two rotary cylinders, the hot wavy wall could be cooled faster and the Nusselt number will increase. Furthermore, the rotation direction of cylinders is determinant regarding the rate of heat transfer.