Supplementary Fig. S6 from Phase Ib Pharmacodynamic Study of the MNK Inhibitor Tomivosertib (eft508) Combined with Paclitaxel in Patients with Refractory Metastatic Breast Cancer

Supplementary Fig. S6: Translatomic profiling. UpSet plots display overlap of the translationally downregulated (A) and upregulated (B) mRNAs between each patient. The numbers above the bars represent the number of mRNAs that exclusively belonged to the conditions marked below the bars. The horizontal bar graph on each plot's left side shows the number of differentially translated mRNAs in each patient.