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    Medical laboratory method for diagnosis of intrathecal immunoglobulin synthesis in which free kappa or lambda immunoglobulin light chains in the cerebrospinal fluid are quantitatively measured

    PL460627A
    发明人
    ARNETH BORROS M
    受让人
    ARNETH B M (ARNE-Individual)
    申请人
    Shinji Isokawa, Tomoji Yamaguchi
    申请号
    17038389
    申请日
    2022-01-28
    公开(公告)号
    PL460627A
    公开(公告)日
    2020-11-02
    IPC分类号
    B01J19/18B01J19/00
    CPC分类号
    -
    优先权号
    000047
    396004
    优先权日
    2002-01-09
    2003-01-09
    摘要

    본 발명은 다중 모세관 구조의 형태를 갖는 가스, 바람직하게는 수소 가스 저장 시스템에 관한 것이다. 이러한 다중 모세관 구조는 특정 길이에 걸쳐 일정한 단면을 가지며, 이러한 단면은 다중 모세관이 충분히 가요성을 갖는 값으로 급격히 감소된다. 다중 모세관의 가요성 영역은 수소를 연료 전지로 수송하기에 충분한 길이를 갖는다. 이러한 방식으로, 가요성을 갖는 다중 모세관 가스 파이프 라인이 생성되는데, 이러한 파이프 라인은 대량의 수소 정장 공간과 통합됨으로써, 이에 의해 연료 전지에 수소를 공급하도록 구성된다. 구체적으로, 본 발명의 목적은 고압 가스를 갖는 다중 모세관 탱크의 신속 재충전과 더불어 다중 모세관 탱크로부터 매니 폴드로 제어된 가스 방출이 가능한 연료 가스 저장 시스템을 제공하는 것으로, 이때 연료 전지의 작동을 위한 적절 압력이 1 MPa 미만으로 유지되도록 구성된다. 가스 저장 시스템 및 연료 전지로의 가스 수송 시스템을 포함하여 동력원의 최적 안전과 더불어 효율적인 중량 및 공간 특성을 보장하는 것이 필요하다.

    权利要求
    1. An arrangement for converting an analog detection signal of a magnetic resonance detection coil into a digital detection signal and for transmitting the digital detection signal to an evaluating device, the arrangement comprising: a detection coil comprising: an analog-to-digital converter operable to digitize the analog detection signal at a first sampling frequency; and a decimation filter operable to decimate the digitized detection signal to a second sampling frequency, wherein the decimation filter comprises a filter portion with a frequency response having a ripple content greater than 1 dB in a pass region associated with a signal of the digitized detection signal; a transmission route operable to carry the digitized detection signal to the evaluating device; and an equalizing filter following the transmission route, the equalizing filter having a frequency response that corresponds to an inverse of the filter portion frequency response in at least the pass region associated with the signal.
    2. The arrangement of claim 1 , wherein the ripple content in the pass region is greater than 5 dB.
    3. The arrangement of claim 2 , wherein the ripple content in the pass region is greater than 12 dB.
    4. The arrangement of claim 1 , further comprising a mixer operable to mix the analog detection signal with a local oscillator frequency, the mixer being connected upstream of the analog-to-digital converter such that the signal input to the analog-to-digital converter is at an intermediate frequency.
    5. The arrangement of claim 4 , wherein a mirror filter is connected upstream of the mixer, an anti-aliasing filter is connected downstream of the mixer, or the mirror filter is connected upstream of the mixer and the anti-aliasing filter is connected downstream of the mixer.
    6. The arrangement of claim 1 , wherein the transmission route comprises a radio link, an optical waveguide, a transmission conductor line, or a combination thereof.
    7. The arrangement of claim 1 , further comprising: a serializer connected upstream of the transmission route; and a deserializer connected downstream of the transmission route.
    8. The arrangement of claim 2 , further comprising a mixer operable to mix the analog detection signal with a local oscillator frequency, the mixer being connected upstream of the analog-to-digital converter such that the signal input to the analog-to-digital converter is at an intermediate frequency.
    9. The arrangement of claim 8 , wherein a mirror filter is connected upstream of the mixer, an anti-aliasing filter is connected downstream of the mixer, or the mirror filter is connected upstream of the mixer and the anti-aliasing filter is connected downstream of the mixer.
    10. The arrangement of claim 3 , wherein the transmission route comprises a radio link, an optical waveguide, a transmission conductor line, or a combination thereof.
    11. The arrangement of claim 4 , wherein the transmission route comprises a radio link, an optical waveguide, a transmission conductor line, or a combination thereof.
    12. The arrangement of claim 3 , further comprising: a serializer connected upstream of the transmission route; and a deserializer connected downstream of the transmission route.
    13. A magnetic resonance device comprising: an arrangement for converting an analog detection signal of a magnetic resonance detection coil into a digital detection signal and for transmitting the digital detection signal to an evaluating device, the arrangement comprising: a detection coil comprising: an analog-to-digital converter operable to digitize the analog detection signal at a first sampling frequency; and a decimation filter operable to decimate the digitized detection signal to a second sampling frequency, wherein the decimation filter comprises a filter portion with a frequency response having a ripple content greater than 1 dB in a pass region associated with a signal of the digitized detection signal; a transmission route operable to carry the digitized detection signal to the evaluating device; and an equalizing filter following the transmission route, the equalizing filter having a frequency response that corresponds to an inverse of the filter portion frequency response in at least the pass region associated with the signal.
    14. The magnetic resonance device as claimed in claim 13 , wherein the detection coil is a local coil.
    15. A method for converting an analog detection signal of a magnetic resonance detection coil into a digital detection signal and for transmitting the digital detection signal, the method comprising: digitizing, with an analog-to-digital converter, the analog detection signal at a first sampling frequency; decimating the digitized detection signal to a second sampling frequency, wherein the decimating has a frequency response with a ripple content greater than 1 dB in a pass region associated with a signal of the digitized detection signal; transmitting the decimated digitized detection signal to an evaluation device, equalizing the decimated digitized detection signal following the transmitting, the equalizing having a frequency response that corresponds to an inverse of the decimating frequency response in at least the pass region associated with the signal.
    16. The method of claim 15 , further comprising increasing a damping in a stop band according to an increase in the ripple content to obtain a pre-defined minimum filter damping difference between a pass band and the stop band.
    17. The method of claim 16 , wherein the pre-defined minimum filter damping difference is 40 dB.
    18. The method of claim 16 , further comprising increasing a word size of the decimated detection signal according to an increase in a dynamic range of the frequency response as compared with a word size of the digitized detection signal.
    19. The method of claim 18 , wherein the word size is increased by 2 bits when the ripple content is 12 dB.
    20. The method of claim 15 , further comprising serializing the decimated digitized detection signal before transmitting, and deserializing the decimated digitized detection signal after transmitting.
    说明书
    [0001]This invention covers a method for treating inner surfaces of conduits, such as conduits of vapour conduction installations, for example, in installations for electric energy production; according to said method a thermal projection device is deployed, through the end or a manhole of a conduit, and it comprises the operations of positioning, centering, possibly verifying the result, and advancing. It also comprises using mechanical, optical, acoustic or electronic means for recognition of any changes in direction of the conduit, and repositioning of the device in respect of said changes in direction.
    [0002]This invention also comprises a device for treatment of inner surfaces of conduits which comprises a thermal projection device, pulling means, possibly means for centering a head for projecting particles of molten metal, pulling means and possibly a system for detecting any changes in direction of the conduit. The device also comprises means for supplying energy and feeding the metal to be projected.
    [0003]Vapour conduits of all kinds of industrial installations, such as vapour conduits of energy production installations, are subject to aggression through abrasion, due to the high speed at which the vapour circulates, and this can be worsened by possible chemical aggression due to the ionisation of the vapour. Over time the abrasion becomes serious and can weaken the conduits. On one hand, these installations are extraordinarily costly, for which reason the replacement of material which can be preserved must be avoided, insofar as this is possible, and on the other, the use of a vapour installation in unsafe conditions proves highly dangerous, since any pore produced in the conduits, apart from a high risk for the safety of any operator who might be affected by the blast given off, would require immediate stoppage of the installation, replacement of the damaged section, and thorough revision of the entire installation, which would entail very high costs. Since there is wear, there has to be a replacement of the material dragged off by the vapour, so as to maintain the initial conditions, or at least safe conditions.
    [0004]STATE OF THE ART
    [0005]U.S. Pat. No. 6,508,413 describes a machine for cleaning and remote coating of a conduit, such as a vapour conduit. This machine comprises a support bar, fitted with associated motors, which comprises motors for the movement of a head along said bar, and for the rotation of the head, said head comprising means for abrasion cleaning and/or thermal projection of metal. It comprises at least one pair of tripods for proper positioning and securing in the pipeline and also comprises a device for control of the device. This device must work in sections, since the device must be repositioned in each of said sections, at the same time as there are zones, such as the zones for support of the tripod legs, which could lead to shortcomings in the coating, and would in any event require the reduction of the distances in which the devices has to be relocated in each new section.
    [0006]SUMMARY OF THE INVENTION
    [0007]This invention refers to a mobile device able to move along a conduit, particularly a horizontal conduit or one with a small slope, which comprises:
    [0008]A moving support; the moving support will be provided with at least one movement motor and possibly a motor on each of the sides; A set of means for pulling said moving support along the surface of the conduit; these pulling means can be wheels, chains or pulling bands; The pulling means are possibly located more or less radially on the centre of the device, and preferably said pulling means are radially extendible for a proper adjustment on the section of the conduit; An operating head set in the front part of the moving support; The operating head is preferably rotary, normally in a 360° arch or a little more, said rotation being limited by the cables and conduits that the device must hold; A device for thermal projection of particles of molten metal; the thermal projection device is set in the operating head; in turn the thermal projection device can be articulated on the operating head on an axis transversal to that of the conduit; At least one means of power supply; the power used can be electric energy, the power supply means consisting in a cable or set of cables inserted in the conduits through the manhole or open end of the conduit, as far as the regeneration device, hydraulic energy and/or pneumatic energy, in these last two cases the corresponding conduits or flexible hoses would be used; A means of supplying the metal to be projected, in the form of wire or wire coils; And possibly: A device for detecting the state of the regenerated surface, understanding state to mean the degree of quality of the coated surface; A display means;
    [0009]BRIEF DESCRIPTION OF THE FIGURES In order to illustrate the following explanation, we are enclosing with this descriptive report three sheets of drawings in which the essence of this invention is represented in six figures, and in which: FIG. 1 shows a schematic view in perspective of a first more simple option of the device for regeneration of inner surfaces of conduits by means of thermal projection of metals according to the invention and FIG. 2 shows a lateral view of the device of FIG. 1 ; FIG. 3 shows a lateral schematic view of a second option of the device according to the invention, in which the body of the device comprises two angularly separated sets of wheel, is expandable and extendible to match the conditions of the conduit, in a retracted position; FIG. 4 shows a lateral schematic view similar to the one in FIG. 3 , but in an expanded and extended position; FIG. 5 shows a front view of the device of FIGS. 3 and 4 , in which one can clearly appreciate the angular separation of the wheels; and FIG. 6 shows a view like the one in FIG. 5 , in which the device is fitted with three sets of wheels.
    [0010]DETAILED DESCRIPTION OF THE PREFERENTIAL FORMS OF EMBODIMENT
    [0011]This invention therefore consists of a method for regenerating inner surfaces of conduits by means of thermal projection of metals, comprising the stages of:
    [0012]Inserting a device carrying the thermal projection means through a manhole in a conduit installation; if the carrying device is expandable, the insertion will be performed with the device retracted; Inserting electrical, pneumatic and/or hydraulic conduits through a manhole, as well as feeding the metal to be thermally projected; Preferably, when the device is ready for this, the expansion of the rolling means to make sure that the device matches the conduit properly; it should normally be ensured that the device is centred in the conduit; When the device is extendible, the extension of a support of a thermal projection device; Movement of the device by remote-control pulling in a particular position to regenerate until this is positioned in the place to be regenerated, including, where applicable, the corresponding fixing; The angle alignment of an operating head placed on the carrying device; The thermal projection of metal from the regeneration device; Rotation along the surrounding annular perimeter, normally approximately 360°, until proper regeneration is achieved, and advancing to a new regeneration position.
    [0013]The method also optionally comprises picking up an image of the inside of the conduit and transmitting the information to a device for recording, viewing or information processing, located on the outside, from which the right decision can be made, such as for a further movement of the carrying device to regenerate a new zone, extraction of the device, or continuation of the projection process if the regeneration has not reached a satisfactory degree.
    [0014]The method is also designed to include, as well as or instead of picking up the graphic image, measuring the thickness of the walls of the conduit or measuring prior to or after the thermal projection phase, determining in either of these cases if the operation has given a sufficiently satisfactory result.
    [0015]This invention also covers a device for regenerating inner surfaces of conduits by the thermal projection of metals, as claimed in claim 4 , which is formed of:
    [0016]A remote-control vehicle ( 1 ), carrying a device for the thermal projection of metals ( 4 ), able to be inserted through a manhole for an installation of conduits such as an installation for energy generation; this vehicle ( 1 ) comprises, in a preferential embodiment, an elongated structure ( 11 ) carrying pulling means and a system for carrying a device for thermal projection of metal; the vehicle ( 1 ) is fitted with a set of wheels or pulling chains ( 2 ); according to the preferential embodiment, the vehicle ( 1 ) comprises at least two trains of wheels ( 22 ) angularly separated by roughly 120°±40°, fitted with at least one front wheel and at least one rear wheel, normally a pair of front wheels and a pair of rear wheels, at least on of the front or rear wheels or pairs of wheels is fitted with a drive motor; each front or rear wheel or pair of wheels will preferably be fitted with a motor with independent drive; optionally, though not preferably, three or more trains of wheels ( 22 ) will be fitted, separated from each other at a suitable angle; in the preferential option each of the trains of wheels is able to be expanded or retracted, so that the dimensions of the device are the very minimum for inserting into the conduit, to then have the proper operating dimensions inside the conduit; An operating head ( 13 ) set on the vehicle, normally at the front (the opposite end to where the cables are connected) able to be positioned and angle-aligned properly in respect of said vehicle, comprising a device for thermal projection ( 4 ) of particles of molten metal; in accordance with a preferential option, the head ( 13 ) is extendible/retractile, for example by means of an endless screw ( 23 ), so that when it is in the operating phase the front end of this head will be at the furthest distance from the body of the vehicle ( 1 ); according to said preferential option; the operating head ( 13 ) is also able to rotate on a longitudinal axis; it is desirable for the rotation to take place at an angle close to 360°, so that in the thermal projection phase the regeneration takes place in the same way over the whole corresponding annular surface; A device for thermal projection ( 4 ); this thermal projection device will normally be hinged on the operating head ( 13 ) on an axis transversal to that of the conduit; Electrical ( 7 ), pneumatic and/or hydraulic connections for supplying, controlling and maneuvering the vehicle ( 1 ) and the head fitted with the thermal projection device ( 4 ) fitted on the remote-control vehicle ( 1 ); A means of supplying the metal to be projected, in the form of wire or wire coils.
    [0017]The rear end of the vehicle may possibly also comprise a securing device ( 14 ) for the cables, wire, or other conduits, and this securing device is preferably able to rotate in synchronisation with the operating head ( 13 ).
    [0018]The device according to the invention is designed to also comprise a device for detecting the thickness and/or the surface evenness of the regenerated surface or also a device for picking up the image inside the conduit and transmitting the information to a device for recording, displaying or information processing.
    [0019]In accordance with a preferential embodiment, the vehicle ( 1 ) comprises an hinged arm ( 3 ), one of whose ends is articulated to this vehicle ( 1 ) by means of a lower hinge pin ( 9 ) and the other in turn holds the operating head by means of an upper hinge pin ( 10 ). Preferably either the hinged arm ( 3 ), or the operating head or both of these comprise a rotation axle perpendicular to the corresponding hinge pin ( 9 , 10 ) which enables the mobility of the head in the rotational direction (rotation in respect of a vertical axis when the operating head is set in a horizontal position).
    [0020]The device disclosed in the invention comprises means of control for adjusting the position of the operating head.
    [0021]In a preferential embodiment, the device for expanding/retracting the wheel trains ( 22 ) takes place by means of a fixed axle ( 31 ) (for each train) fitted in the elongated structure ( 11 ), as well as a corresponding mobile axle ( 32 ) able to be slid along by means of a track ( 33 ); as the axles approach each other, the angle of the corresponding carrying bars in respect of said elongated structure increases, causing the end where the corresponding wheels are located to move away.
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