Background: Various guidance techniques have been developed for optimal pedicle screw placement. We present our initial experience with intraoperative CT (iCT) navigation for transpedicular screw fixation in the thoracolumbar spine. Objective: This study aimed to describe the accuracy and reliability of iCT navigation for transpedicular screw fixation. Material and Methods: One hundred consecutive patients underwent thoracolumbar pedicle screw fixation under iCT navigation. After iCT registration of the local bony anatomy with a firmly attached spinous process tracker, pedicle screw placement was performed under navigation with an infrared camera and infrared reflectors on insertion instruments. Screw trajectories of the intraoperative verification CT were matched against the navigation paths. Radiological and clinical follow-up was prospectively documented and retrospectively analyzed. The study included 47 women and 53 men with a mean age of 66 years. Indications for thoracolumbar pedicle fixation were degenerative instability with stenosis, cyst or disc herniation (82), spondylolytic instability (9), scoliosis with stenosis (6), and traumatic fractures (3). A total of 443 pedicle screws were inserted: 22 in the thoracic spine, 371 in the lumbar spine, and 50 in S1. Results and Conclusions: Four hundred thirty-five out of 443 screws (98%) were correctly placed. Misplacement was explained by loosened infrared reflectors on pedicle awl or probe, or by the displacement of the spinous process tracker; misplaced screws were re-inserted intraoperatively and showed correct placement on the second verification CT. Based on our first 100 cases, iCT navigation for transpedicular screw fixation in the thoracolumbar spine seems to be very accurate and reliable.

Background and Objective We present a treatment approach for a rare condition of patients with a ventral C1 fracture and a congenital cleft in the posterior arch (half-ring Jefferson fracture) with an intact transverse atlantal ligament. Our technique aims to achieve stability of the atlanto-occipital and atlantoaxial joints while preserving mobility of the upper cervical spine. Patients and Methods Two male patients, 43 years and 29 years of age, respectively, were admitted to our hospital due to a fracture of the ventral arch of the atlas with no damage of the transverse atlantal ligament. Both men also presented a congenital cleft of the posterior arch. Initial conservative management with a halo-thoracic vest was performed in one case and failed. As a result, surgical treatment was performed in both cases using bilateral C1 mass screws and a transverse connector. Results The patients showed no neurologic deficits on follow-up examination 4 weeks after surgery with a full range of head and neck motion. Computed tomography (CT) showed no dislocation of the implanted material with good dorsal alignment and a stable ventral fracture distance. Follow-up CT showed osseous stability in both cases with the beginning of bony ossification of the bone graft. Conclusion Isolated instable fractures of the ventral arch of the atlas with a congenital cleft of the posterior arch with no damage of the transverse atlantal ligament can be stabilized using bilateral C1 mass screws and a transverse connector preserving upper cervical spine mobility.

Idiopathic spinal cord herniation (ISCH) is a rare spinal disease, in which chronic cerebrospinal fluid pulsations push the arachnoid and adjacent thoracic spinal cord region through an antero-lateral dural defect of congenital, post-traumatic, or inflammatory/erosive origin. Symptomatic patients commonly present around the 5th decade of life with slowly progressive myelopathy. Diagnosis relies on high-resolution magnetic resonance imaging. Stable mild cases may be observed, whereas in progressive symptomatic situations, surgical spinal cord reposition and dural defect repair with a dural patch is the preferred treatment. We present a case of ISCH at T5/6 and a review the literature.

Background: The Magerl transarticular technique and the Harms-Goel Cl lateral mass-C2 isthmic screw technique are the two most commonly used surgical procedures to achieve fusion at C1-C2 level for atlanto-axial instability. Despite recent technological advances with an increased safety, several complications may still occur, including vascular lesions, neurological injuries, pain at the harvested bone. graft site, infections, and metallic device failure.Methods: We retrospectively analyzed all patients (n 42 cases) undergoing a Harms-Goel C1-C2 fixation surgery with polyaxial Cl lateral mass screws and C2 isthmic screws at two different institutions between 2003 and 2012 and report clinical and radiological complications. One patient was lost to follow-up. The mean follow-up of the remaining 41 patients was 18.7 months (range 12-90). A clinically relevant complication was defined as a complication determining the onset of a new neurological deficit or requiring the need for a revision surgery.Results: A total of 14 complications occurred in 10 patients (24.4% of 41 patients). Greater occipital nerve neuralgia was evident in 4 patients (9.8%). All but one completely resolved at the end of the follow-up. Persistent neck pain was reported by 3 patients (7.3%). hypoesthesia by 1 patient (2.4%), and anesthesia in the C2 area on both sides in 1 patient (2.4%). Furthermore, a superficial, a deep, and a combined superficial and deep wound infection occurred in 1 patient each (2.4%). One patient (2.4%) had pain at the iliac bone graft donor site for several weeks with spontaneous resolution. A posterior progressive intestinal herniation through the iliac scar was seen in 1 case (2.4%), which required surgical repair. No vascular damages occurred. Altogether, 5/41 patients (12.2%) had a clinically relevant complication including 4 patients necessitating a revision surgery at the C1-C2 level (9.8%).Conclusions: Atlanta-axial fixation surgery remains a challenging procedure because of the proximity of important neurovascular structures. Nevertheless, on the basis of our current experience, the Cl lateral mass-C2 isthmic screw technique appears to be safe with a low incidence of clinically relevant complications. Postoperative C2 neuralgia, as the most frequent problem, is due to surgical manipulation during preparation of the Cl screw entry point. (C) 2014 Elsevier B.V. All rights reserved.

Acute traumatic central cord syndrome (ATCCS) is the most common type of incomplete spinal cord injury, characterized by predominant upper extremity weakness, and less severe sensory and bladder dysfunction. ATCCS is thought to result from post-traumatic centro-medullary hemorrhage and edema, or, as more recently proposed, from a Wallerian degeneration, as a consequence of spinal cord pinching in a narrowed canal. Magnetic Resonance Imaging is the method of choice for diagnosis, showing a typical intramedullary hypersignal on T2 sequences. Non-surgical treatment relies on external cervical immobilization, maintenance of a sufficient systolic blood pressure, and early rehabilitation, and should be reserved for patients suffering from mild ATCCS. Surgical management of ATCCS consists of posterior, anterior or combined approaches, in order to achieve spinal cord decompression, with or without stabilization. The benefits of early surgical decompression in the setting of ATCCS remain controversial due to the lack of clinical randomized trials; recent studies suggest that early surgery (less than 72hours after trauma) appears to be safe and effective, especially for patients with evidence of focal anatomical cord compression.

BACKGROUND:Different treatment options exist for symptomatic single-level degenerative anterolisthesis and stenosis. While simple micro-decompression has been advocated lately, most authors recommend posterior decompression with fusion. In recent years, decompression and dynamic transpedicular stabilisation has been introduced for this indication. The aim of this study was to evaluate the safety and efficacy of decompression and dynamic transpedicular stabilisation with the Dynesys® system in single-level degenerative anterolisthesis and stenosis.METHODS:Thirty consecutive patients with symptomatic single-level degenerative anterolisthesis and stenosis without scoliosis underwent decompression and single-level Dynesys stabilisation at the level of degenerative anterolisthesis. Patients were followed prospectively for 24 months with radiographs, Oswestry Disability Index scores, visual analogue scale (VAS) for back and leg pain, and estimated pain-free walking distance.RESULTS:At the 2-year follow-up, back pain was reduced from 6.5 preoperatively to 2.5, leg pain from 5.4 to 0.6. The pain-free walking distance was estimated at 500 m preoperatively and at over 2 km after 2 years, while the ODI decreased from 54 % to 18 %. Screw loosening was found in 2/30 cases. Symptomatic adjacent segment disease was found in 3/30 patients between 12 and 24 months postoperatively.CONCLUSIONS:Single-level Dynesys stabilisation combined with single- or multi-level decompression seems to be a safe and efficient treatment option in single-level degenerative anterolisthesis and stenosis over an observation period of 2 years, avoiding iliac crest or local bone grafting required by fusion procedures. However, it does not seem to avoid adjacent segment disease.

Purpose: SPECT fused with computed tomography (CT) provides a new approach for more accurate diagnosis of pseudathrosis after spinal fusion procedures. The aim of this study was to compare the findings of SPECT fused with CT (SPECT/CT) with those of CT alone for the diagnosis of pseudarthrosis.Materials and Methods: SPECT and CT of 10 consecutive patients with recurrence of back and/or leg pain and with suspicion of pseudarthrosis on conventional radiologic imaging were analyzed retrospectively. All had previously undergone anterior and/or posterior lumbar fusion techniques. Presence of screw loosening, nonunion through or around the cages, and facet joint degeneration were assessed for diagnosis of pseudarthrosis. Based on SPECT/CT scan findings, the decision of surgical reintervention was made on 6 of 10 patients. The clinical follow-up (mean, 15.6 months; range, 5-29 months) was evaluated according to Macnab criteria (excellent, good, fair, poor).Results: All patients showing screw loosening on CT alone showed also an abnormal uptake on SPECT/CT. SPECT/CT did not show abnormal uptake in 3 of 5 patients who had nonunion through/around the cages on CT alone. SPECT/CT was able to show increased uptake in 6 cases in which CT alone did not show facet joint degeneration.Conclusions: In the lumbar spine, SPECT/CT seems to increase specificity for detection of nonunion of interbody devices compared with CT alone. It is more sensitive than CT to detect facet joint degeneration, and it can detect screw loosening as well as CT. These findings can be helpful for surgeons in planning appropriate surgical revision strategy.

Extradural arachnoid cysts of the spine are a rare cause of spinal cord and nerve root compression, usually in the mid to lower thoracic spine and at the thoraco-lumbar junction in a posterior position. Local pain and myelopathy occur predominantly in young adults, and MRI reveals a well-demarcated extradural lesion, iso-intense to cerebrospinal fluid. We report a 33-year-old woman with an extradural arachnoid cyst from T11 to L1 and review the surgical techniques reported in the literature.

Background Minimal-access technology has evolved rapidly with "tubular" or "percutaneous" approaches for decompression and stabilization in the lumbar spine. Potential benefits (smaller scars, diminished local pain, reduced blood loss, reduced postoperative wound pain, shorter hospital stays) have to be weighed against possible drawbacks (reduced orientation, steep learning curve, increased radiation exposure, dependency on technology, cost). While non-comparative case series are often rather enthusiastic, comparative studies and particularly RCTs are scarce and might convey a more realistic appreciation.Methods A MEDLINE search via PubMed was performed to find all English-language studies comparing "open" or "traditional" or "conventional" with "minimally invasive" or "percutaneous" or "tubular" approaches in degenerative lumbar spine surgery.Results Only nine comparative studies could be retrieved altogether. No clear benefit could be found for minimally invasive procedures in lumbar disc herniation, TLIF, or PLIF. There seems to be a slight advantage in terms of hardware safety in open procedures.Conclusions This review, based solely on the very limited number of available comparative studies, shows no relevant benefit from minimally invasive techniques, and a tendency for more safety in open procedures in lumbar disc herniation, TLIF and PLIF.

The C1 lateral mass and C2 isthmic stabilization, as introduced by Goel and Laheri and by Harms and Melcher, is a well-known fixation technique. We present the clinical and radiographic results with freehand fluoroscopy guided C1 lateral mass and C2 isthmic fixation in a consecutive series of 28 patients, evaluating the accuracy of screw placement.

ABSTRACT A cefoxitin-susceptible Staphylococcus aureus strain was identified by the Cepheid GeneXpert as methicillin-resistant S. aureus (MRSA). This strain was highly unstable and rapidly lost SCC mec upon subculturing in vitro , indicating that unstable MRSA is best detected by gene amplification-based methods.

Superficial siderosis of the central nervous system is a rare disorder with hemosiderin deposition in the spinal and cranial leptomeninges and subpial layer, mostly from repetitive subarachnoid hemorrhage. Progressive sensorineural deafness, cerebellar ataxia, and pyramidal signs comprise the typical clinical presentation. We describe a 47-year-old patient, who showed initial 2-year improvement after successful occlusion of an intradural bleeding source at T4. Secondary progression of symptoms without further bleedings was noted thereafter, with a clinical picture of amyotrophic lateral sclerosis. This case illustrates that the disease may progress secondarily even without re-bleedings, and that secondary progression might be due to a similar pathomechanism as in amyotrophic lateral sclerosis.

Spontaneous idiopathic acute spinal subdural hematomas are highly exceptional. Neurological symptoms are usually severe, and rapid diagnosis with MRI is mandatory. Surgical evacuation has frequently been used therapeutically; however, spontaneous recovery in mild cases has also been reported. We present a case of spontaneous recovery from severe paraparesis after spontaneous acute SSDH, and review the English-speaking literature.

The book Spine Surgery—Tricks of the Trade by AlexanderVaccaro and Todd Albert, Second Edition, definitely holdstrue to its title. On a little over 300 pages of this hardcoverbook, over 80 authors, mainly from the USA but also fromother countries, have put together a fascinating overview ofmodern spine surgery techniques. As stated in the title, thisbook is fostering on the technical aspects of spinal surgeryand is not a text book about spinal disease.The book is extremely well structured with systematicdescriptions of posterior then anterior approaches, eachfirst without instrumentation then with instrumentation,from the craniovertebral junction down to the sacrum.Special sections about deformity, minimally invasiveprocedures, bone grafting, external immobilization,motion-preserving procedures, and complication manage-ment follow to round up the spine surgeon's potentialarmamentarium. The last section “Complications Manage-ment” is particularly useful to busy spine surgeons asdealing with complications and awareness of their bestmanagement is often neglected in the current literature ascomplications are generally under-reported.Each surgical procedure is described in the samesystematic manner with the subheadings: “Description”,“Key principles”, “Indications”, “Contraindications”,“Special Considerations”, “Special instructions/position/anesthesia”, “Tips/pearls and lessons learned”, “Difficul-ties encountered”, “Key procedural steps”, “Bailout/rescue/salvage procedures”, and “Pitfalls”. The letter sizeis somewhat small and needs careful reading but seemsnecessary to confine text length to about 3–5 pages pertechnique on average, which maintains excellent over-view. Furthermore, this book is probably not designed forsystematic read-through but rather for a pinpointed work-up or brush-up of one or more specific procedures.Again, the clear structure here makes it a pleasure to findand read through the chapter(s) needed. The illustrationsfit well into the chapter, and though only black andwhite, they are clear and instructive. The index is helpfuland clear. There are no references; rather, the authors ofeach procedure chapter are listed directly below the titleof the chapter.As spinal surgery has impressively evolved over the pasttwo decades, it is of paramount importance not to lose theoverview of available surgical solutions and to know theirpros and cons. This is exactly what this book offers: onlyvery little (and understandable!) bias is noted in thetechnical descriptions by the authors. Rather, a useful self-critical style has been implicated by such subheadings as“Difficulties encountered”, “Bailout/rescue/salvage proce-dures”, and “Pitfalls”. Such a differentiated presentation ofstrengths and weaknesses of procedures will allow theneurosurgical or orthopedic resident, spine fellow, or fullytrained specialist to make his or her own and besttherapeutic choice in a given situation.

C1-C2 instability or painful osteoarthritis are recognised indications for posterior atlanto-axial fixation. In the traditional trans-articular C1-C2 screw fixation, up to 20% of patients cannot have safe placement of bilateral screws in the event of a medially located vertebral artery and a straight screw trajectory in the sagittal plane. The more recently developed C1-C2 fixation technique with individual C1 lateral mass screws and converging C2 pars screws can be employed in case of a medially located vertebral artery and has comparable biomechanical strength. This is a prospective observational study to investigate the advantages, the safety, and the drawbacks of posterior atlanto-axial fixation with polyaxial C1 lateral mass screws and C2 pars screws.Twelve consecutive patients with C1-2 instability (n = 11) and painful osteoarthritis (n = 1) underwent a posterior atlanto-axial fixation with polyaxial C1 lateral mass screws and C2 pars screws. The average follow-up was 16 months and all patients reached the 12-month follow-up.No hardware failure occurred in any of the patients. Correct screw placement and construct stability was found in all 12 patients (100%) at 6 and 12 months after surgery. Mean neck pain on a visual analogue scale (VAS) was 2.1 at 6 months and 2.0 at 12 months. Only transient complications were observed: one patient presented with progressive intestinal herniation through the iliac crest scar; one suffered from severe pain at the posterior iliac crest for 3 months and three patients complained of annoying pain/dysaesthesia in the C2 dermatome for 3-6 months after surgery.This study confirms that posterior atlanto-axial fixation with polyaxial C1 lateral mass screws and C2 pars screws is a safe and effective surgical option in the treatment of atlanto-axial instability or painful osteoarthritis.

Spinal epidural abscess (SEA) is a rare infection of the spinal peridural space, usually from haematogenous spread of bacteria from a distant source of infection or from direct extension of an osteomyelitis or paravertebral abscess into the spinal canal. An extensive SEA with involvement of five or more levels is even more exceptional and is a very threatening condition. Different surgical strategies have been used in the typically posteriorly located extensive SEA: multi-level laminectomies at all involved levels; catheter procedures, in which suction (irrigation) catheters are pushed cranially and caudally through selected end-level and intermediate-level fenestrations or laminectomies; or multi-level interlaminar fenestrations at the involved levels. We report the evacuation of a 14-vertebral-level cervico-thoracic SEA by multi-level unilateral fenestrations with 'over-the-top' removal of contralateral abscess formations at all involved levels. We also discuss the surgical strategies for extensive SEA.

Background: Traditional open anterior approaches to the TL spine were reported with a significant morbidity from a large wound field; therefore, "minimally invasive" thoracoscopic and laparoscopic anterior approaches have been recently introduced. However, these endoscopic techniques require a long and steep learning curve, require expensive disposable endoscopy material, and may be little suited for complication management. Alternatively, "mini-open" anterior approaches with table-mounted retractor systems have also been recently introduced.Methods: Thirty-seven patients underwent a single-level thoracic or lumbar corpectomy and cage reconstruction for an unstable traumatic burst fracture or vertebral body tumor. A transthoracic (n = 6), transthoracic transdiaphragmatic (n = 23), or retroperitoneal (n = 8) mini-open approach was conducted with the SynFrame (Stratec Medical, Oberdorf, Switzerland) table-mounted retractor. Prior posterior pedicle screw fixation was performed in 35 of 37 patients.Results: The mean surgical duration of the anterior approach was 181 minutes, and the average blood loss was 632 mL. There was no neurological worsening. On a VAS from 0 to 10, the mean local pain from the anterior approach was 1.7 at 6 months postoperatively, 1.4 at 12 months, and 1.0 at 24 months. Construct stability was found in all patients at 6 months after surgery. Six transient complications occurred.Conclusions: The mini-open anterior approach for corpectomy in the TL spine is safe, reliable, and economical. The table-mounted SynFrame retractor provides a stable operating field through which a familiar direct 3-dimensional view of the anterior TL spine is obtained with limited approach morbidity. This technique is an excellent alternative to thoracoscopic or laparoscopic procedures, avoiding the steep learning curve, technical difficulties, and equipment costs of endoscopic procedures. (C) 2008 Elsevier Inc. All rights reserved.