AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

A simple method has been developed for obtaining esters of benzimidazolyl-1-acetic acid and its 2-alkyl (or aralkyl) derivatives, by reaction of benzimidazoles with esters of chloroacetic or bromoacetic acid in DMF in the presence of anhydrous potassium carbonate. The method of synthesis of amides of these acids has been simplified.

Derivatives of pyrrolo[1,2a]benzimidazolyl-4-acetic add have been synthesized by quaternization of 2-alkyl(aralkyl)benzimidazolyl-1-acetic acids and their esters and amides by α-bromoketones, followed by cyclization of the resulting 1,2,3-substituted benzimidazolium bromides by the action of sodium alcoholate, ammonia, amines (primary, secondary, or tertiary), or hydrazine hydrate.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Chemischer InformationsdienstVolume 8, Issue 27 Heterocyclic Compounds ChemInform Abstract: STUDIES ON IMIDAZOLES. XCII. REDUCTION OF SOME DERIVATIVES OF PYRROLO(1,2-A)IMIDAZOLE AND PYRROLO(1,2-A)BENZIMIDAZOLE A. A. DRUZHININA, A. A. DRUZHININASearch for more papers by this authorP. M. KOCHERGIN, P. M. KOCHERGINSearch for more papers by this authorR. M. PALEI, R. M. PALEISearch for more papers by this authorO. N. MINAILOVA, O. N. MINAILOVASearch for more papers by this author A. A. DRUZHININA, A. A. DRUZHININASearch for more papers by this authorP. M. KOCHERGIN, P. M. KOCHERGINSearch for more papers by this authorR. M. PALEI, R. M. PALEISearch for more papers by this authorO. N. MINAILOVA, O. N. MINAILOVASearch for more papers by this author First published: July 5, 1977 https://doi.org/10.1002/chin.197727209Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume8, Issue27July 5, 1977 RelatedInformation

Chemischer InformationsdienstVolume 8, Issue 13 Heterocyclic Compounds ChemInform Abstract: STUDIES ON IMIDAZOLES. LXXXIX. REACTION OF 1-ALKYL-2-CYANO(ALKOXYCARBONYL)METHYL DERIVATIVES OF IMIDAZOLE AND BENZIMIDAZOLE WITH α-HALO KETONES P. M. KOCHERGIN, Search for more papers by this authorA. A. DRUZHININA, Search for more papers by this authorR. M. PALEI, Search for more papers by this author P. M. KOCHERGIN, Search for more papers by this authorA. A. DRUZHININA, Search for more papers by this authorR. M. PALEI, Search for more papers by this author First published: March 29, 1977 https://doi.org/10.1002/chin.197713240Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume8, Issue13March 29, 1977 RelatedInformation

The effect of the temperature and the acidicity of the medium on the ratio of the two tautomeric forms of the conjugate acids of derivatives of indolizine, pyrrolo[1,2-a]imidazole, and pyrrolo[1,2-a]benzimidazole was investigated by PMR spectroscopy. The change in the ratio of the forms with time was studied under fixed reaction conditions. The position of the tautomeric equilibrium in a number of the investigated systems was established. A correspondence between the relative stabilities of the protonated forms and the rate constants for electrophilic deuterium exchange in the neutral molecules was observed.

The closeness of the electronic structures of the ions formed in the first act of disintegration of the ions is responsible for the monotypic character of the subsequent fragmentation of pyrrolo[1,2-a]benzimidazole and imidazo[1,2-a]benzimidazole derivatives. The mass-spectrometric disintegration of the investigated systems has something in common with the fragmentation of thiazolo[3,2-a]benzimidazole derivatives.

Chemischer InformationsdienstVolume 4, Issue 3 Physical Organic Chemistry ChemInform Abstract: DIE PROTONIERUNG VON DERIVATEN DES PYRROLO(1,2-A)BENZIMIDAZOLS L. M. ALEKSEEVA, L. M. ALEKSEEVASearch for more papers by this authorG. G. DVORYANTSEVA, G. G. DVORYANTSEVASearch for more papers by this authorI. V. PERSIANOVA, I. V. PERSIANOVASearch for more papers by this authorYU. N. SHEINKER, YU. N. SHEINKERSearch for more papers by this authorR. M. PALEI, R. M. PALEISearch for more papers by this authorP. M. KOCHERGIN, P. M. KOCHERGINSearch for more papers by this author L. M. ALEKSEEVA, L. M. ALEKSEEVASearch for more papers by this authorG. G. DVORYANTSEVA, G. G. DVORYANTSEVASearch for more papers by this authorI. V. PERSIANOVA, I. V. PERSIANOVASearch for more papers by this authorYU. N. SHEINKER, YU. N. SHEINKERSearch for more papers by this authorR. M. PALEI, R. M. PALEISearch for more papers by this authorP. M. KOCHERGIN, P. M. KOCHERGINSearch for more papers by this author First published: January 16, 1973 https://doi.org/10.1002/chin.197303066AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume4, Issue3January 16, 1973 RelatedInformation

The protonation of a number of pyrrolo[1,2-a]benzimidazole derivatives in trifluoroacetic acid was studied by PMR spectroscopy. 1,3-Unsubstituted compounds are protonated exclusively at the C1 atom. Under similar conditions, pyrrolobenzimidazoles that have a methyl group in the 1 position form a mixture of two protonated forms, which correspond to the addition of a proton to C1 and C3, respectively. The relative percentage of the C3-protonated form decreases successively (from 81 to 18%) on passing from the 3-unsubstituted compound to the corresponding 3-phenyl and 3-methyl derivatives. The basicity constants of the pyrrolobenzimidazoles decrease symbatically with an increase in the relative percentage of this form. The relative proton-acceptor capacity of indolicine, pyrrolo[1,2-a]-imidazole, and pyrrolo[1,2-a]benzimidazole were examined on the basis of the protonation data and the reactivity indexes, calculated by the simple Hückel MO method.