Advanced oxidation processes using persulfate (PS) have proven effective in degrading organic pollutants in water. The key to these processes is the development of catalysts that efficiently activate PS. Single-atom catalysts (SACs), where individual metal atoms are dispersed on a solid support, offer superior catalytic activity compared to traditional metal catalysts and hold great promise. In this study, we synthesized a tungsten-based SAC (W-SA-g-C3N4) by anchoring tungsten onto graphite-like carbon nitride (g-C3N4) for sulfadiazine (SDZ) degradation in water. The results showed that single-atom tungsten was mainly incorporated into the g-C3N4 in the W6 + state, which created more active sites for PS activation and enhanced electron migration. More than 92.3% of SDZ was decomposed within 60 min in the W-SA-g-C3N4/PS system, and appropriate catalyst dosage and solution pH favored SDZ decomposition processes. The presence of Cl−, SO42−, and NO3− had slight impacts on SDZ degradation efficiency, and over 85% of ciprofloxacin, norfloxacin, and oxytetracycline could also be removed in the W-SA-g-C3N4/PS system. Radical scavenger and EPR experiments identified 1O2 and •O2− as key species in SDZ degradation. The SDZ degradation processes mainly involved the fragmentation of the benzene ring and associated clusters. Additionally, the catalyst exhibited excellent stability and recyclability.

Fluorinated organic pollutants pose significant environmental and health risks due to the high stability of C─F bonds, necessitating effective strategies for their degradation. Herein, we present a bilayer WO 3 photoelectrode (double-WO 3 ) incorporating an electron transport layer (ETL) and a hexagonal-monoclinic heterophase junction for PEC degradation of fluorinated pollutants. The double-WO₃ catalyst achieves a high photocurrent density (4.3 mA cm −2 at 1.2 V RHE ) and nearly complete degradation (99.9%) of bisphenol AF (BPAF), 4-fluorophenol (4-FP), and pentafluorophenol (PFP), with 99.9% mineralization of PFP. Experimental and transient photocurrent (TPC) analyses confirm that the ETL-heterophase junction structure enhances electron extraction and surface reaction kinetics while minimizing electron-hole recombination. In this process, photogenerated h⁺ excites fluorinated pollutants, enhancing C─F bond susceptibility to ∙OH attack, which facilitates bond cleavage and subsequent oxidation into CO 2 , H 2 O, and F − . This study offers a promising strategy for designing advanced PEC systems and effectively remediating persistent fluorinated contaminants.

Photoelectrocatalytic (PEC) degradation of organic pollutants in wastewater is a promising approach to address water pollution problems. However, the performance of most reported PEC degradation systems is heavily limited by electron-hole recombination and sluggish surface reaction kinetics. Herein, we report a TiO2 nanocone array photoanode modified by the NiO cocatalyst (denoted as NiO-TiO2), which displays a greatly enhanced performance in PEC degradation of phenolic compounds. The kinetic studies suggest that the supported NiO cocatalyst can facilitate water dissociation on the TiO2 electrode. The spectroscopic studies show that loading the NiO cocatalyst is beneficial for charge separation. As a result, the PEC performance of NiO-TiO2 for the degradation of 4-chlorophenol (20 ppm) is enhanced, with a degradation efficiency of 99.0% and a mineralization efficiency of 49.1% at 1.0 V vs RHE. The rate constant for the surface degradation reaction on NiO-TiO2 is 2.31 min-1 m-2 ppm g, which is 2.1 times that for the TiO2 photoelectrode. This work indicates that modification of a semiconductor photoelectrode with a cocatalyst can not only boost surface reaction kinetics but also promote charge-transfer dynamics, thereby increasing the PEC activity in the degradation reactions of pollutants.

Development of photoelectrodes capable of efficiently degrading fluorinated pollutants with C-F bonds remains a significant challenge in the photoelectrocatalytic (PEC) system. Herein, a nanoneedle CoOOH-loaded nanoplate WO3 photoelectrode (CoOOH/WO3) was successfully fabricated, which exhibited a high rate of 3.92 x 10-2 min-1 in the PEC degradation of 4-fluorophenol, much higher than that of pristine WO3. The center dot OH generation rate by CoOOH/WO3 was 1.5 times that by WO3. Photoelectric features demonstrated that an interfacial internal- electric field provided a driving force for efficient charge separation in the CoOOH/WO3; Density functional theory calculations demonstrated that constructing CoOOH onto WO3 reduced thermodynamic barriers for H2O oxidation and for *OH formation, thereby promoting the center dot OH generation; Computational fluid dynamic simulations confirmed the facilitated surface reactions and intensified contact between pollutants and center dot OH. This study provided viable insights into simultaneously improving the charge separation efficiency, surface H2O oxidation kinetic and physical contact in PEC wastewater treatment.

The most crucial factors limiting the degradation performance of photoelectrocatalytic (PEC) process are the low charge separation efficiency and slow mass transportation. Herein, we report a WO3 network photoelectrode by constructing heterophase junction of WO3 on tungsten mesh (hm-m-WO3/W mesh), which exhibits superior PEC performance, as high as 5.6 mA cm(-2) of photocurrent density at 1.2 V-RHE, achieving a complete degradation (99.9%) and nearly total mineralization (84.5%) of bisphenol A, reaching an apparent reaction rate constant of 5.7 x 10(-2) min(-1), 1.5 times of WO3 based photoelectrode ever reported. A Schottky junction is formed at m-WO3/W interface which greatly promotes the charge transfer between catalysts and support. The catalysts show appropriate phase alignment, where the parallel directions between built-in electric field of heterophase junction and external potential benefit charge separation. Computational fluid dynamics simulations indicate the network structure favors the diffusion of the fluid containing pollutants. This work demonstrates a viable strategy for designing the photoelectrode with high charge separation efficiency and fast mass transportation in PEC wastewater treatment.

Photoelectrocatalytic (PEC) degradation of organic pollutants into CO2 and H2O is a promising strategy for addressing ever-growing environmental problems. Titanium dioxide (TiO2) has been widely studied because of its good performance and environmental benignancy; however, the PEC activity of TiO2 catalyst is substantially limited due to its fast electron-hole recombination. Herein, we report a TiO2 nanocone-based photoelectrocatalyst with superior degradation performance and outstanding durability. The unique conical catalyst can boost the PEC degradation of 4-chlorophenol (4-CP) with 99% degradation efficiency and higher than 55% mineralization efficiency at a concentration of 20 ppm. The normalized apparent rate constant of a nanocone catalyst is 5.05 h-1 g-1 m2, which is 3 times that of a nanorod catalyst and 6 times that of an aggregated particle catalyst, respectively. Further characterizations reveal that the conical morphology of TiO2 can make photogenerated charges separate and transfer more efficiently, resulting in outstanding PEC activity. Moreover, computational fluid dynamics simulations indicate that a three-dimensional conical structure is beneficial for mass transfer. This work highlights that tuning the morphology of a photoelectrocatalyst at the nanometer scale not only promotes the charge transfer but also facilitates the mass transportation, which jointly enhance the PEC performance in the degradation of persistent pollutants.

Photoelectrocatalytic (PEC) degradation of organic pollutants into CO2 and H2O is a promising strategy for addressing ever-growing environmental problems. Titanium dioxide (TiO2) has been widely studied because of its good performance and environmental benignancy; however, the PEC activity of TiO2 catalyst is substantially limited due to its fast electron–hole recombination. Herein, we report a TiO2 nanocone-based photoelectrocatalyst with superior degradation performance and outstanding durability. The unique conical catalyst can boost the PEC degradation of 4-chlorophenol (4-CP) with 99% degradation efficiency and higher than 55% mineralization efficiency at a concentration of 20 ppm. The normalized apparent rate constant of a nanocone catalyst is 5.05 h–1 g–1 m2, which is 3 times that of a nanorod catalyst and 6 times that of an aggregated particle catalyst, respectively. Further characterizations reveal that the conical morphology of TiO2 can make photogenerated charges separate and transfer more efficiently, resulting in outstanding PEC activity. Moreover, computational fluid dynamics simulations indicate that a three-dimensional conical structure is beneficial for mass transfer. This work highlights that tuning the morphology of a photoelectrocatalyst at the nanometer scale not only promotes the charge transfer but also facilitates the mass transportation, which jointly enhance the PEC performance in the degradation of persistent pollutants.

Magnetic AC@CoFe2O4 nanocomposites (decoration of activated carbon with CoFe2O4 nanoparticles) as an efficient persulfate (PS) activator were successfully prepared through a facile co-precipitation method. The crystalline, morphology and textural properties of the composites were characterized. Then the catalytic performances of as-synthesized AC@CoFe2O4 were investigated towards PS activation for the degradation of lomefloxacin (LMF). Results demonstrated that the sample prepared at a 1:1 mass ratio of AC (activated carbon) to CoFe2O4 possessed higher catalytic activity owing to the synergistic interactions between these two components. The maximum LMF degradation of 98.4% and the pseudo first-order kinetic constant of 0.03796 min(-1) were achieved after 60 min reaction at the optimized operation conditions: 0.2 g.L-1 of AC@ CoFe2O4 and 1 g.L-1 of PS, pH of 5.0 and reaction temperature of 25 degrees C. The free radical quenching experiments and XPS analysis were undertaken to illustrate the proposed mechanism, which indicated that the SO(4)(center dot- )and HO center dot were the predominant radicals involved in LMF degradation. Moreover, the Co(II), Fe(II) and oxygenated functional groups participated in the PS activation process. Subsequently, several oxidation intermediates were identified and five suggested pathways were proposed to reveal the reaction mechanism, indicating a comprehensive route of LMF decomposition via the activation of PS. AC@CoFe2O4 also displayed good reusability and magnetic property, which would hold great potential in the persulfate-based treatment of antibiotic contaminated wastewater.

Activated carbon coated with CoFe layered double hydroxide (AC@CoFe-LDH) as an efficient catalyst of activating persulfate (PS) for the degradation of lomefloxacin (LMF) was successfully prepared and characterized. Various effects of reaction parameters on LMF degradation including PS dosage, catalyst concentration, initial pH and temperature were systematically studied. Results indicated that AC@CoFe-LDH nanocomposites exhibited ultra -high activity for PS activation compared with bare AC, modified AC (AC-HCl) and CoFe-LDH, in which 93.2% of LMF could be removed within 60 min by the AC@CoFe-LDH with an AC to CoFe-LDH ratio of 1:1 activating PS. It was also found that the condition of 1.gL(-1) ps, 0.2 g.L-1 catalyst, solution pH of 5 and reaction temperature of 25 degrees C was optimized. In the reaction system, both SO4 center dot- and HO center dot were responsible for the LMF degradation and SO4 center dot- was the primary one. The cycles of Fe(II)/Fe(III) and Co(M/Co(III) were confirmed by XPS analysis which revealed the proposed mechanism for PS activation. Moreover, AC@CoFe-LDH nanocomposites with good stability and recyclability showed great potential for the oxidative treatment of organic contaminants.

at and after the time of a complete cytogenetic response(CCR) predict the duration of CCR in imatinib mesylatetreated patients with CML[J]. Blood, 2006, 107(11):4250-4256. DOI: 10.1182/blood-2005-11-4406. [10] Deininger M, O’Brien SG, Guilhot F, et al. International randomized study of interferon vs STI571(IRIS)8-year follow up: Sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase(CML-CP)treated with imatinib[J]. Blood(ASH annual meeting abstract), 2009, 114(22): 462. [11] Druker BJ, Guilhot F, O'Brien SG, et al. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia[J]. N Engl J Med, 2006, 355(23):24082417. DOI: 10.1056/NEJMoa062867. [12] Kantarjian H, Shah NP, Hochhaus A, et al. Dasatinib versus imatinib in newly diagnosed chronicphase chronic myeloid leukemia[J]. N Engl J Med, 2010, 362(24):22602270. DOI: 10.1056/NEJMoa1002315. [13] Porkka K, Khoury HJ, Paquette RL, et al. Dasatinib 100 mg once daily minimizes the occurrence of pleural effusion in patients with chronic myeloid leukemia in chronic phase and efficacy is unaffected in patients who develop pleural effusion [J]. Cancer, 2010, 116(2):377-386. DOI: 10.1002/cncr.24734. [14] Hagihara M, Iriyama N, Yoshida C, et al. Association of pleural effusion with an early molecular response in patients with newly diagnosed chronicphase chronic myeloid leukemia receiving dasatinib: Results of a DFirst study[J]. Oncol Rep, 2016, 36 (5):2976-2982. DOI: 10.3892/or.2016.5110. [15] Eliasson L, Clifford S, Barber N, et al. Exploring chronic myeloid leukemia patients' reasons for not adhering to the oral anticancer drug imatinib as prescribed[J]. Leuk Res, 2011, 35 (5):626-630. DOI: 10.1016/j.leukres.2010.10.017. [16] Marin D, Bazeos A, Mahon FX, et al. Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib[J]. J Clin Oncol, 2010, 28(14):23812388. DOI: 10.1200/JCO.2009.26.3087. (收稿日期:2019-11-30) (本文编辑:王叶青)

Magnetic CuO/MnFe2O4 nanocomposite were synthesized and characterized as a heterogeneous catalyst. Subsequently, it was used to activate persulfate (PS) for levofloxacin (LVF) removal with the operating parameters optimized. Results reveled that the sample of CuO/MnFe2O4-9% showed higher catalytic performance than pure CuO, pure MnFe2O4 and other fabricated CuO/MnFe2O4 nanocomposites. And under the optimized conditions of 1 g center dot L-1 CuO/MnFe2O4-9% and PS at pH 9 and 25 degrees C, 91.3% of LVF could be decomposed within 120 min. Besides, the underlying mechanism of CuO/MnFe2O4 nanocomposite activating PS was proposed by free radical quenching experiment and XPS results. Eventually, several degradation intermediates of LVF were identified and three decomposition pathways were proposed. Especially, the CuO/MnFe2O4 nanocomposite exhibited superparamagnetic property and good stability, which favored the catalyst to be efficiently recovered through the applied magnetic field and reused from aquatic environment. Thus, the as-prepared CuO/MnFe2O4 nanocomposite might be applied to the removal of refractory organics in environmental remediation.

In this study, gamma-Fe2O3/alpha-MnO2 nanocomposite, which possesses magnetism as well as excellent activation performance for potassium persulfate (PS) to degrade organic contaminants in water, was successfully fabricated through ultrasonic strategy. Noted, proportion between gamma-Fe2O3 and alpha-MnO2 was optimized to achieve excellent magnetic and activation performance. Also, physicochemical properties of magnetic nanocomposite material (gamma-Fe2O3/alpha-MnO2 1/7, FM1-7) are investigated by SEM, EDS, BET, XRD, TEM, XPS and vibrating sample magnetometer (VSM). Results show that gamma-Fe2O3 nanoparticles is connected with alpha-MnO2 nanorods successfully, what's more, FM1-7 nanocomposite crystal structure is intact and its crystallinity is excellent. Besides, in gamma-Fe2O3/alpha-MnO2/PS reaction system, about 92.79% of Rhodamine B could be removed within 30 min. The result proves that when the gamma-Fe2O3 content is 12.5%, gamma-Fe2O3/alpha-MnO2 nanocomposite exhibits superior activation performance. gamma-Fe2O3/alpha-MnO2/PS reaction shows the most excellent degradation towards Rhodamine B when it is compared with another reaction systems. Most importantly, in this study, the crucial role of gamma-Fe2O3 and catalysis mechanism of gamma-Fe2O3/alpha-MnO2 is also discussed in detail. In the Fenton-like system mediated by Fe(III) and Mn(IV), the redox reactions with the activation of PS happen on the surface of gamma-Fe2O3/alpha-MnO2. Therefore, strong oxidizers of SRs (SO4 center dot-), hydroxyl radicals ((OH)-O-center dot) and even superoxide anion (O-center dot(2)-) may be generated and participated in the degradation of Rhodamine B. What's more, the result of repetitive experiment illustrates that magnetic FM1-7 sample possesses good recycle and reusability capacities. This study not only provides a feasible strategy to prepare catalyst which could be used to active PS, but also is expected to be applied to deal with many kinds of contaminants removal problem according to the practical requirement.

In the study, visible-light active Ti3+ doped TiO2 nanorods/nanosheets (Ti3+/TiO2 NRs/NSs) photoelectrode was successfully fabricated by hydrothermal reaction, followed by sodium borohydride reduction treatment. Moreover, physicochemical properties of the resulting samples were studied by series" of techniques. Also, photocatalytic (PC) activity of Ti3+/TiO2 NRs/NSs photoelectrode was measured by degradation of methylene blue (MB). Results suggested that Ti3+ and oxygen vacancies (Ov) were simultaneously formed and induce the formation of impurity energy level in the TiO2 NRs/NSs band gap by solution reduction treatment, which exerted a huge influence on the photocatalytic and photoelectrochemical properties of Ti3+7/TiO2 NRs/NSs photoelectrode in the mean time. Furthermore, Ti3+/TiO2 NRs/NSs photoelectrode exhibited higher PC activity (89.61%) than that of pristine TiO2 NRs/NSs (73.56%) within 150 min visible light illumination owing to the enhancement of visible light harvesting and separation efficiency of photoproduced charges. Moreover, the possible enhanced PC mechanism of Ti3+/TiO2 NRs/NSs was proposed and confirmed. Furthermore, Ti3+/TiO2 NRs/NSs photo electrode displayed good stability and reusability.

There is an increasingly significant issue on decomposition of contaminants in modem chemical industry and environmental protection. Hence, in the study, to improve the catalytic of semiconductor materials, the silver silver bromide nanoparticles decorated reduced TiO2 nano-tube arrays photoelectrode (Ag-AgBr/r-TiO2 NTAs), which exhibits better photocatalytic (PC) performance in the wide range of solar spectra, was successfully fabricated by anodization process, followed by microwave reduction strategy. The partly reduced AgBr nano particles are decorated and both Ti3+ and states are simultaneously introduced in the TiO2 NTAs photo electrode inducing the formation of impurity energy level to form Ag-AgBr/r-TiO2 NTAs photoelectrode. Moreover, PC activity of Ag-AgBr/r-TiO2 NTAs photoelelctrode was measured by degradation of 4-chlorphenol (4-CP). Results suggest that Ag-AgBr/r-TiO2 NTAs photoelectrode exhibits higher PC activity (99.9%) than that of other samples within 120 min illumination. The well combination of surface plasmons Ag-AgBr nanoparticles and r-TiO2 NTAs was responsible for the enhancing of PC, and the recombination of photo-generated electrons and holes can simultaneously be inhibited. Thus, Ag-AgBr nanoparticles and Ti3+ exert huge influence on the PC and photoelectrochemical properties of Ag-AgBr/r-TiO2 NTAs photoelectrode.

In the study, CeO2 nanoparticles were successfully decorated on the TiO2 nanotube arrays (CeO2/TiO2 NTAs) photoelectrode by cathodic electrodeposition method in the presence of Ce(NO3)(3) electrolyte. The effect of fabricating parameters including electrolyte concentration, applied voltage, deposition time and calcination temperature on morphology and crystal structure of CeO2/TiO2 NTAs was further investigated. Moreover, the as prepared materials were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscope (SEM). Meanwhile, the optical and photoelectrochemical (PECH) properties were recorded through ultraviolet-visible diffuse reflectance spectroscopy (UV-vis DRS), transient photocurrent response (i-t) and open circuit potential (OCP), respectively. Furthermore, we evaluated the electrical catalysis (EC), photocatalytic (PC) and photoelectrochemical (PEC) performances of the CeO2/TiO2 NTAs photoelectrode by degradation of methyl orange (MO). Results indicated that the CeO2/TiO2 NTAs exhibited higher EC, PC and PEC activities than that of pristine TiO2 NTAs photoelectrode owing to higher separation of efficiency photo produced electrons-holes (e/h(+)) pairs and visible light absorption.

In the research, reduced TiO2 nano-tube arrays (denoted as R-TiO2 NTAs) photoelectrode was successfully fabricated by potassium borohydride (PBH) reduction treatment. Afterwards, the as-fabricated photoelectrode was characterized by scanning electron microscope, X-ray diffraction, Raman spectra and electron spin resonance. Meanwhile, the optical and photoelectrochemical properties of R-TiO2 NTAs photoelectrode were also studied through ultraviolet-visible diffuse reflectance spectroscopy and transient photocurrent response, respectively. The photocatalytic (PC) activity of R-TiO2 NTAs photoelectrode was measured by degradation of trichlorophenol (TCP). Moreover, the change of toxic intermediates in the process of degradation TCP was further evaluated by photobacterium inhibition tests. Results suggested that an impurity level can be induced in the TiO2 NTAs band gap by solution reduction treatment due to the generation of Ti3+ and oxygen vacancies (Ov). Furthermore, R-TiO2 NTAs photoelectrode exhibited higher PC activities than that of pristine TiO2 NTAs owing to the enhancement of visible light harvesting between 450 and 800 nm and separation efficiency of photogenerated electrons-holes (e/h(+)) pairs. The possible pathway for TCP degradation and photocatalytic mechanism were also proposed and confirmed. Furthermore, R-TiO2 NTAs photoelectrode displayed good stability and reusability. (C) 2017 Taiwan Institute of Chemical Engineers. Published by Elsevier B.V. All rights reserved.

As a non-steroidal anti-inflammatory drug, diclofenac, was commonly used as analgesic, antiarthritic and antirheumatic, and has frequently been detected in municipal wastewater treatment plants (MWTPs) effluents and demonstrated to be potentially environmental risk on human beings. In the present study, N, S co-doped TiO2 nano-crystallites decorated TiO2 nano-tube arrays (N, S-TiO2 NCs/TiO2 NTAs) photoelectrode was used to degrade diclofenac containing wastewater. In addition, the effects of some critical parameters including initial pH, external positive potential, sodium sulfate concentration and initial diclofenac concentration on the photoelectrocatalytic (PEC) degradation of diclofenac containing wastewater and dynamic characteristics were investigated systematically. Results showed that N, S-TiO2 NCs/TiO2 NTAs photoelectrode exhibited high PEC efficiency for the degradation of diclofenac, in which the PEC processes fitted well with the Langmuir-Hinshelwood (L-H) model. Furthermore, external additional anions such as Cl-, ClO- and NO3- played an important role in inhibiting the degradation of diclofenac. Also, the N, S-TiO2 NCs/TiO2 NTAs photoelectrode possessed good stability for consecutive applications for degradation of diclofenac, which could potentially be utilized in wastewater treatment.

In this study, silver decorated graphene oxide (Ag/GO) composite was fabricated through a reduction process in the presence of potassium borohydride solution. Subsequently, physicochemical properties of the resulting Ag/GO composite were studied by scanning electron microscope, X-ray diffraction, Raman spectra, Fourier transformation infrared spectroscopy and UV-visible diffuse reflectance spectrum. Results indicated that Ag species existed in the form of Ag0, which greatly facilitated the visible light absorbance ability. Furthermore, the performance of Ag/GO was evaluated by PC inactiviation of Escherichia coli under Xenon lamp illumination. It was found that Ag/GO sample could kill the Escherichia coli within 60 min illumination by the non-selective attack of ⋅OH radicals. This study provides a novel and facile strategy to fabricate high-efficient catalyst to kill the bacteria in drinking water treatment.

In this work, magnetic gamma-Fe2O3/Mn3O4 nanocomposites with various mass ratios were successfully fabricated using a facile two-step method. Then these composites were characterized using X-ray diffraction (XRD), scanning electron microscope (SEM), transmission electron microcopy (TEM), X-ray photoelectron spectra (XPS) and vibrating sample magnetometer (VSM) measurements. Besides, the samples were applied to activate per sulfate for Rh B degradation. Results showed that the sample with a gamma-Fe2O3/Mn3O4 mass ratio of 3:1 exhibited higher activity than other gamma-Fe2O3/Mn3O4 nanocomposites, pure gamma-Fe2O3 and pure Mn3O4, where 95.1% of Rh B could be decomposed within 150 min in the presence of persulfate. In addition, effects of operational parameters on the catalytic activity of Rh B were also evaluated, which included persulfate concentration, catalyst dosage, reaction temperature and initial pH value. More importantly, the as-fabricated gamma-Fe2O3/Mn3O4 nanocomposites revealed magnetism and could be separated conveniently through external magnetic, which was beneficial to recycle the catalysts from the aqueous solution. Finally, the mechanism of activating persulfate by gamma-Fe2O3/Mn3O4 nanocomposites was proposed based on the results and literatures, which might provide a reference for further study of heterogeneous catalysis.

In the present work, the photocatalytic performance of P25TiO2 was investigated by means of the degradation of aspirin, while the reaction system was systematically optimized by central composite design (CCD) based on the response surface methodology (RSM). In addition, three variables of initial pH value, initial aspirin concentration and P25 concentration were selected to assess the dependence of degradation efficiencies of aspirin. Meanwhile, a predicted model of degradation efficiency was estimated and checked using analysis of variance (ANOVA). The results indicated that the PC removal of aspirin by P25 was significantly influenced by all these variables in descending order as follows: P25 concentration > initial aspirin concentration > initial pH value. Moreover, the parameters were optimized by the CCD method. Under the conditions of an initial pH value of 5, initial aspirin concentration of 10 mg/L and P25 concentration of 50 mg/L, the degradation efficiency of aspirin was 98.9%with 60 min of Xenon lamp irradiation. Besides, based on the liquid chromatography-mass spectrometry measurements, two main PC degradation pathways of aspirin by TiO2 were deduced and the tentative degradation mechanism was also proposed.