<正>多囊卵巢综合征(polycystic ovary syndrome,PCOS)是女性常见的生殖内分泌疾病,其发生率占生育年龄妇女的5%～10%,在育龄期尤以生殖障碍者居多。现代医学认为,PCOS是由下丘脑—垂体—卵巢轴系统功能失调引起,临床表现为月经稀发,无排卵,不孕,高雄激素血症,肥胖,血清黄体生成激素(LH)水平升高,组织学显示双侧卵巢呈多囊性改变。西医治疗副反应较多,可能加重内分泌紊乱,引起卵泡过度刺激征等严重并发症,以及高促排卵率、低妊娠率。王佩娟为江苏省中医药研究院、江苏省中西医

The causes of premature ovarian failure are complex,and autoimmunity is an important reason causing premature ovarian failure.T lymphocytes can be divided into helper T cells,cytotoxic T cells and regulatory T cells according to their function.Research shows that premature ovarian failure is closely related with T lymphocyte subsets.However,there is no agreement about the relationship between premature ovarian failure and each subset of T lymphocytes.Especially the connection between premature ovarian failure and helper T cells and cytotoxic T cells is controversial,and there is no report about premature ovarian failure and regulatory T cells.Therefore,it is particularly significant to explore the relationship between autoimmune premature ovarian failure and T lymphocyte subsets.