OBJECTIVE: To promote rational drug use through intervention on perioperative utilization of antibacterials in inpatients undergoing breast surgery.METHODS: The perioperative utilization of antibacterials in inpatients undergoing breast surgery in Apr.2007(before intervention) was compared with that in the same period in 2008(after medication intervention) with regard to the medication time and duration of antibiotics,number of kinds of antibiotics and consumption sum etc.RESULTS: Compared with before intervention,significant differences were noted after the intervention with regard to the time and duration of medication,varieties and consumption sum of antibiotics.CONCLUSION: The intervention promoted rationality in application duration of antibiotics,decreased the consumption sum of antibiotics,and shortened patients' hospital stay.However,the choice of antibiotics remains to be improved.

乳腺癌是女性中常见的恶性肿瘤,全球每年约有120万妇女患乳腺癌,50万人死于该疾病.据国家卫生部信息中心公开资料显示,在沿海城市如上海等地区,乳腺癌发病率居女性肿瘤第一位,每年有12万～15万名乳腺癌患者需要观察和治疗.

AIM: To establish quality standard for Compound Shengui Capsules. METHODS: Glycyrrhiza uralensis Fisch.、Panax notoginseng(Burk.) F.H.Chen、Salvia miltiorrhiza Bge.and Ligusticum chuanxiong Hort.were identified by TLC.Ammonium glycyrrhizinate and tanshinoneⅡ_A were determined by HPLC.(RESULTS): (TLC) spots developed were fairly clear and the blank test showed no interference.The linear rangers were 0.5-4μg(r=0.999 8)for ammonium glycyrrhizinate;0.04-0.32μg(r=0.999 6) for tanshinoneⅡ_A.The average recoveries of them were 98.9%,97.8%,respectively. CONCLUSION: The methods is effective for the quality control of Compound Shengui Capsules.