[Objective]To study the epidemiological feature of the occurrence and development of pneumoconiosis and provide basis for improving medical preventive measures against pneumoconiosis.[Methods]793 cases of lately diagnosed pneumoconiosis cases from 1963 to 2007 in Luoyang were studied and analyzed.[Results]Most of the pneumoconiosis cases were from the field of coalmine(46.28%),glass material(21.06%)and mineral(14.38%).The works of cases were mainly digging coal(35.31%)and moulding(22.32%).The diagnosed pneumoconiosis cases were mainly distributed after 1980.The patients with pneumoconiosis in Luoyang were mainly silicosis(49.18%)and collier pneumoconiosis(46.28%).The patients with pneumoconiosis were mainly distributed in stage Ⅰ.The average spell of sickness from stage Ⅰ to stage Ⅱ was 7.48 years and from stage Ⅱ to stage Ⅲ was 10.46 years.The age of patients suffering from stage Ⅰ and duration of dust expose in silicosis were all significantly shorter as compared with those in collier pneumoconiosis(P﹤0.05).The case mortality rate of silicosis in stage Ⅱ and stage Ⅲ increased significantly as compared with collier pneumoconiosis(P﹤0.05).The case mortality rate of silicosis and collier pneumoconiosis increased significantly with stage(P﹤0.001).The main proportional mortality were pneumocardial(20.22%)and pneumoconiosis(19.13%).[Conclusion]The main areas to be strengthened in their prevention measures on pneumoconiosis might be pneumocardial.The main industries to be focused on might be coalmine,mineral and glass material.Collier pneumoconiosis and silicosis are key factors among pneumoconiosis cases.Hygienic supervision should be strengthened.Early diagnosing and controlling syndromes are the critical measures to the restoration.

Objective To learn the death of pneumoconiosis patients in Luoyang and provide basis for improving medical preventive measures against pneumoconiosis. Methods Analysis was carried out on the causes of death,disease categories,industrial distribution,time distribution,spell of sickness and stage distribution. Results The main proportional mortality was pneumocardial and pneumoconiosis.Collier pneumoconiosis occupied 46.99% and silicosis 45.90% among the total death number.86.88% of the pneumoconiosis death cases were from the field of coalmine,mineral,mechanism and glass material.Coalmine that occupied 48.63% was in the first place among all of them.The death number of silicosis increased with time and the collier pneumoconiosis was opposite to it.The average spell of sickness of silicosis was 7.02 years;collier pneumoconiosis was 9.87 years and other pneumoconiosis was 7.43 years.The death number of pneumoconiosis and pulmonary tuberculosis increased with stage and others were opposite to them. Conclusion The main areas to strengthen their prevention measures on pneumoconiosis might be pneumocardial.The main industries to be focused on might be coalmine,mineral,mechanism and glass material.Collier pneumoconiosis and silicosis are key factors among pneumoconiosis death cases.Hygienic supervision should be strengthened.Early diagnosing and controlling syndrome are the critical measure to the restoration.

鸡新城疫（ND）和鸡的传染性支气管炎病（IB）仍然是目前养鸡业的最大病害。国内外虽已研制出许多良好的疫苗，但由于近年来变异株和超强毒的出现以及ND和IB混感率的不断上升，现在应用的ND和IB疫苗普遍存在以下弊端：（1）疫苗毒株与当地流行毒不相吻合，免疫效果不佳；（2）ND和IB疫苗分别接种，常造成应激反应而影响免疫应答；（3）油佐剂灭活苗的免疫产生速度不够理想。为此，1996～1997年对当地鸡病进行流行病学调查，在对致病毒株分离鉴定的基础上，试图选用与本地抗原性相似的国际标准毒株作为制苗毒株，研制ND—IB（双价）二联油剂灭活疫苗。