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1Exploration on the Reference Values and Predicted Equation of FIV1 in Normal Adults in Shanghai

胡芸倩,毛培文,艾自胜, 梁永杰

Objective To investigate the predicted value and clinical reference range of the FIV1 in the normal adults in Shanghai.Methods A survey in 521 healthy adults was carried out in Shanghai.FIV1 was measured by using Yager Master Screen difiusion(SN:694855).Explore the reference value and medical reference range.Analyse the relative on the FIV1 and age,weight,height in nomal adults.Results The lung functional parameter FIV1 have positive correlation with height and age,and the height and FIV1 realte closely.While,FIV1 is not related to the weight.The FIV1 predicted equation of normal adult males isFIV1--5.351+0.061 * height-0.027 * age (height,age,P ＜0.001,weight,P ＞0.05),medical reference range is 2.107 5 ～ 4.959 1.The FIV1 predicted equation of normal adult females is FIV1-2.457 + 0.04* height-0.025* age (height,age,P＜0.001,weight,P＞0.05),medical reference range is 1.278 3 ～ 3.517 1.Conclusions FIV1 is related to height and age.The Reference Values and Predicted Equation of normal adults is established and recommended in Shanghai area.

2013

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2Pharmacodynamic Investigation of Rifampicin , Linezolid and Glycopeptide Antibiotics Against Methicillin-Resistant Staphylococcus Aureus

尹琦,张雯雁,叶杨芹,沈李花,毛培文,梁永杰

Objective To compare the selective power of anti-drug-resistant mutant of vancomycin , teicoplanin , linezolid and rifampicin to methicillin-resistant Staphylococcus aureus (MRSA) .Methods The minimum inhibitory concentration (MIC) to MRSA was determined by E-test method. Mutant prevention concentration (MPC) was measured by mix-bacterial method (the inoculated bacterial concentration1×1010CFU/mL) .Selection index (MPC/MIC) and the ratio of MPC to target maximum serum concentration (MPC/Cmax) of the four antibiotics were compared.Results MIC values of vancomycin , teicoplanin , linezolid and rifampin against MRSA were 0.5,1.0,0.5and≤0.5μg/mL; MPC values were 51.2, 25.6 , 9.6and 1024.0 μg/mL ; Selection indices were 102.4 , 25.6 , 19.2and2 048.0; MPC/Cmax were 1.28 , 0.57 , 0.64 and107.80 , respectively.Conclusion Linezolid and teicoplanin have narrower mutant selection window than vancomycin and rifampin , and they have obvious advantages in preventing bacterial antibiotic resistance.

2013引用：23

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3Comparitive Study on Two Ways in Preventing and Curing Navelbine Induced Phlebitis

黄萍,毛培文,蔡碧琴, 莫忠云,汪蜀

化疗是治疗恶性肿瘤的重要手段.诺维本(NVB)又名异长春花碱,是半合成第三代长春花碱,对晚期非小细胞肺癌(NSCLC)疗效优于其他长春碱类药物[1].其主要的毒副反应是对血管的严重损伤,导致化学性静脉炎的发生,使用不当可引起严重非外渗性静脉炎[2],因此护理人员根据不同病人的情况选择有效的防治静脉炎的方法,并进行了对比性研究.

2004引用：8

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