目的 探讨中医特色护理在氯氮平所致精神分裂症便秘患者中的应用效果.方法 选取2017年1月—2019年10月医院收治的精神分裂症患者200例为研究对象,按照组间基线资料可比的原则,分为对照组和观察组,各100例.对照组给予常规护理干预,观察组在对照组的基础上给予中医特色护理干预,比较两组患者干预前后的便秘情况、生活质量.结果 干预后,两组便秘评分降低,SF-36评分升高,且观察组便秘评分低于对照组,SF-36评分高于对照组,差异均有统计学意义(P<0.05).结论 中医穴位贴敷联合耳穴压豆治疗精神分裂症患者可有效缓解便秘症状,提升生活质量和改善心理状态.
探究文拉法辛用于抑郁症治疗的临床效果.将符合本次研究标准的84例抑郁症患者分为2组,对照组42例服用舍曲林,研究组42例服用文拉法辛.比较汉密顿抑郁量表(HAMD)评分、血清单胺类神经递质水平、生活质量量表(SF-36)评分、不良反应情况.治疗后2组HAMD评分较治疗前明显变小(P＜0.05),且治疗后研究组HAMD评分明显小于对照组(P＜0.05);治疗后2组多巴胺、去甲肾上腺素、5-羟色胺水平均高于治疗前(P＜0.05),且治疗后研究组上述血清单胺类神经递质水平明显高于对照组(P＜0.05);治疗后2组SF-36各维度评定分值均大于治疗前(P＜0.05),且治疗后研究组SF-36各维度评定分值明显大于对照组(P＜0.05);2组不良反应发生率比较差异无统计学意义(P＞0.05).抑郁症治疗使用文拉法辛,抑郁程度明显减轻,血清单胺类神经递质水平趋于合理范围,生活质量大幅改善,且安全性高.
OBJECTIVE:To compare the efficacy differences between acupoint catgut-embedding combined western medicine (ACCWM) and simple western medicine (WM) for treatment of epilepsy of generalized seizures type.METHODS:Fifty-two patients with epilepsy of generalized seizures type were randomly divided into an ACCWM group (n=30) and a WM group (n=22). Dazhui (GV 14), Yaoshu (GV 2), Jiuwei (CV 15), Qihai (CV 6) were selected in the ACCWM group as the main acupoints combined with routine antiepileptic drugs, Valpromide was taken orally, 2.0 g/d for adult, 50 mg/kg x d for child. The WM group was treated with routine antiepileptic drugs. The epilepsy score and the attack frequency one year before the treatment and one year during treatment were observed and the therapeutic effects in the two groups were compared.RESULTS:The epilepsy score and the attack frequency were both decreased in the two groups (P<0.01, P<0.05), and the epilepsy score in the ACCWM group decreased significantly (6.57 +/- 3.29 vs 10.73 +/- 2.54, P<0.05). The total effective rate of 90.0% (27/30) in the ACCWM group was superior to that of 68.2% (15/22) in the WM group (P<0.05).CONCLUSION:The therapeutic effect of ACCWM is superior to that of simple western medicine in treating epilepsy of generalized seizures type. It can improve significantly the attack symptoms so as to enhance life quality of the patients with epilepsy.
