Objective To evaluate the long-term outcomes and quality of life after surgery in children and adolescents with temporal lobe epilepsy.Methods Clinical data of 31 children and adolescents with temporal lobe epilepsy were analyzed retrospectively.Surgery was performed in all the patients,including the standard anterior temporal lobectomy in 26,extended anterior temporal lobectomy in 2,standard anterior temporal lobectomy plus malacic focus resection in 2 and resection of posteriotemporal and subparietal epileptogenic focus in 1.The improvements of epileptic seizure,cognition and life quality were evaluated after surgery.Results During a follow-up period of more than 5 years,the patients achieved seizure-free and Engel class I outcome in 26,Engel Ⅱ in 1,Engel Ⅲ in 2,Engel Ⅳ in 2.The postoperative pathological examination showed as follows: hippocampal sclerosis in 13 patients,cortical dysplasia and gliosis in 9,cortical dysplasia and hippocampal sclerosis in 6,glioneuronal tumor in 2 and secondary scar gyrus formation in 1.Most postoperative complications were cured.Conclusion The long-term outcome is good and the quality-of-life could be improved after surgery for temporal lobe epilepsy in children and adolescents.

<正>病例资料:付某,女,54岁,主因"头部剧烈疼痛8年余"于2012年6月21日入院入院。患者8年前无明显诱因出现右侧枕部疼痛,疼痛呈持续性、刀割样,随后波及至同侧额颞顶部,枕部仍为持续性、刀割样疼痛,额、顶、颞部为持续性胀痛,2年前疼痛又波及至右肩部;1年前出现左枕、颞、顶部疼痛,每次为先右侧疼痛发作,后出现左侧疼痛。患者自诉近几年来面容变化较大,呈肢端肥大症面容,于1年前行头颅

<正>前言神经生理学的方法,可以用来研究正常生理情况下的疼痛及其传导、感知和皮层控制的机制;也可以用来评估病理情况下的神经病理痛。电生理技术可以用来指导治疗操作,验证治疗有效还是无效;或通过神经生理学监测(如应用于有潜在神经损伤风险的手术中)来降低疼痛的进展。生理条件下,伤害性感受器受到刺激,信息通