目的 探讨晚期鼻咽癌患者调强放疗治疗的2年生存率及其预后影响因素.方法 选取本院收治的晚期鼻咽癌患者80例为研究对象,患者均接受调强放射治疗(IMRT).放疗结束4周后,评估放疗效果;随访2年,分析患者的2年生存情况,对影响患者预后的因素进行单因素和多因素Logistic回归分析.结果 放疗结束4周后,患者的肿瘤控制率为88.75％;放疗结束后2年患者无进展生存率为65.0％、总生存率为77.5％.多因素Logistic回归分析结果显示,年龄、肿瘤T分期及N分期是影响晚期鼻咽癌患者预后的独立因素,姑息性手术治疗是改善患者预后的保护因素.结论 调强放疗治疗晚期鼻咽癌患者可获得较高的肿瘤控制率;高龄、T分期、N分期是晚期鼻咽癌患者预后的独立影响因素,姑息性手术治疗有助于改善患者预后.

目的 探析术前调强适形放疗对局部晚期直肠癌临床疗效的影响.方法 选择我院2010年1月～2013年10月收治93例局部晚期直肠癌患者进行回顾性分析,根据治疗方式分为新辅助放疗组(52例)与手术组(41例).新辅助放疗组于术前予以调强适形放疗,之后予以手术,手术组直接行根治术.比较两组临床完全缓解率(cCR)、病理完全缓解率(pCR)、2年无病生存率(DFS)、总生存率(0S)、并发症发生率及治疗前后KPS评分.结果 新辅助放疗组cCR、pCR、DFS、OS分别为15.4％(8/52)、9.6％(5/52)、88.5％(46/52)、98.1％(51/52),均高于手术组,差异有统计学意义(P＜0.05),提示近、远期疗效均更佳.新辅助放疗组并发症发生率为11.5％ (6/52),明显低于手术组29.3％(12/41),差异P＜0.05.两组治疗前KPS评分的差异(P＞0.05),治疗后新辅助放疗组KPS评分升高至(88.3±4.3)分,高于手术组(83.7±3.9)分,差异有统计学意义(P＜0.05).结论 术前调强适形放疗治疗局部晚期直肠癌利于破坏肿瘤氧供、缩小瘤体,可大幅提高病理学缓解率并减少术后并发症,利于远期疗效提高.

Objects To explore the resina draconis therapeutics effective in gerontal patients with the pressed sore.Methods 36 patients were divided into the two groups,the therapeutic group with 36 patients amounted up to 56 parts of pressed sore and the controlled one with 18 patients totaled 56 parts of pressed sore.Blended the resina draconis powder with yellow rice wine into pasty and spread it onto the raw surface even in the patients of therapeutic group,norfloxacin powder in the patients of controlled group,then observed the effective in two groups.Results Times of chang dressings were obviously decreased,the healing time shortened.The effective rate in the therapeutic group was 98.2%,the effective rate in controlled one 82.6%.Significance variability existed in two groups,P0.05.Conclusions To use the resina draconis capsule is secure and utility,applied with ease.It works fairly to administrated the resina draconis capsule in gerontal patients with the pressed sore.

目的:探讨在中晚期肝癌患者中介入术后并发症护理的重点.方法:回顾性分析了本院2005年3月～2007年9月期间行经肝动脉化疗栓塞术治疗的中晚期肝癌病人共240例,均在术后给予密切观察生命体征变化,加强动脉穿刺点护理,对术后所出现的并发症进行严密监测和护理,并及时干预.结果:介入术后患者常见并发症为发热、腹痛、黄疸、腹水、恶心、呕吐,不同程度低蛋白血症等.对术后并发症病情的密切观察和及时准确的护理,可以增强病人的心理恢复,有助于并发症的及时处理,早期康复.结论:加强中晚期肝癌患者介入术后护理,对介入治疗术后并发症快速恢复,及时阻止并发症的继续恶化和使病人早日康复具有十分重要的意义.

目的 探讨食管癌颈段高位狭窄患者置入支架治疗的护理重点.方法 回顾性分析了本院2002年7月～2006年3月期间行支架置入治疗食管癌颈段高位狭窄的病人共20例,均在术前及术后给以心理护理,加强饮食护理,对术后所出现的并发症进行严密监测和护理,并及时干预.结果 支架置入术患者常有焦虑及恐惧心理,术后并发症为疼痛、支架再狭窄、支架脱落或移位,反流性食管炎等.术后密切观察并发症的发生和相应的护理,可以增强病人的心理恢复,有助于并发症的及时处理,早期康复.结论 加强对支架置入治疗食管癌颈段高位狭窄患者的护理,对支架的顺利置入及对术后并发症快速恢复,及时阻止并发症的继续恶化和使病人早日康复具有十分重要的意义。

Objective To investigate the effect of nursing intervention on the cancer patient in chemotherapy with cancer-related fatigue (CRF). Methods 100 breast cancer patients with CRF in chemotherapy were randomly divided into the treatment group and the contrcl group. The control group only received conventional nursing care and the treatment group also received systematic nursing intervention of CRF.Brief Fatigue Inventory, EPRTC-QLQ-C30, and KPS were used for evaluating the patients quality of life (QOL) and functional condition separately 15 days pre-and post intervention. Results There was no significant deference between degree of fatigue,QOL and functional condition before intervening(P>0.05). However,there was a significant difference between them 15 days after interference(P<0.05). Conclusions Systematic nursing intervention better than conventional measures only. Health propaganda and education,psychological supporting treatment, aerobic exercise ,nutrition support, et al, could alleviate fatigue and improve the patients" quality of life

objective To explore the effect about nursing intervention on combined radiotherapy and chemotherapy of advanced Nasopharyngeal carcinoma.Methods 110 cases of stage Ⅲ nasopharyngeal carcinoma were randomly assigned to study group which was combined radiotherapy and chemotherapy and control group was subjected to radiotherapy simply . To study the therapeutic efficacy and toxic side effects .according to different toxic side effects we adopted corresponding nursing measures and observed the effects.Results All cases could smooth complete therapy according to plan but toxic side effects in the studying group were worse that of the control group .the patients can relieve their psychogyical press and toxic side effects when they were given the positive nursing measures short- term effects showed the same CR rate of the primary nasopharyngeal focus (p0.05 ).Long-term effects showed the CR rate of neck lymphatic metastasis focus and 5-year survival rate in the study group were higher than that of the control group.Conclusion Combined radiotherapy and chemotherapy could significantly increase the short-term effects and 5-year survival rate but the toxic side effects were severe .Nursing measures could mobilize the patients subjective positive factors and improve the patients who cooperated and received therapy. It was reduced radialized oral mucositis and skin reaction and prevented or decreased complication. It was an important action to smooth complete all therapy and improve the effect