目的炎性因子的表达与骨-肌腱结合点损伤的关联性, 得出促进骨-肌腱结合点愈合的方法及参考依据.方法96只家养成年大白兔作为本次研究对象, 96只成年大白兔分别在术后2、4、8周取材, 根据取材时间的差异将96只成年大白兔分为A(2周)、B(4周)、C(8周)三组, 每组32只.对三组大白兔术后进行放射学、组织学、双抗夹心亲和生物素化酶复合物-酶联免疫吸附试验(ABC-ELISA)检测. 结果 A组和B组在动物血清检测中发现炎性因子白细胞介素-1(IL-1)、白细胞介素-6(IL-6)、白细胞介素-17(IL-17)的表达明显升高, 术后3项炎性因子的表达水平明显高于术前, 术前和术后的3项炎性因子表达不同, 差异有统计学意义(P<0.05).C组成年大白兔的动物血清中3项炎性因子的表达与术前差异无统计学意义(P>0.05).结论 炎性因子表达与骨-肌腱结合点损伤关联性极强, 研究血清中的IL-1、IL-6、IL-17 3项炎性因子的表达情况能够加快骨-肌腱结合点损伤愈合提供科学的参考依据.

Objective To discuss the mechanism of bone-tendon junction healing from the imaging point of view, and to evaluate the value of imaging in the study of bone-tendon junction healing. Methods Thirty New Zealand adult rabbits, aged 17 weeks, were randomly divided into the control group and the periosteum group, with 15 rats in each group. Five rabbits were selected each 5, 9, 13 weeks after surgery in the two groups for histological and radiographic testing. Results Histological examination and imaging examination can clearly reflect the relevant healing mechanism of the periosteum group and the control group after surgery. Five and 9 weeks after surgery, the healing of the periosteum group was faster than that of the control group. New bone was involved in the reconstruction and bone remodeling stage 13 weeks after surgery. The healing of new bone in the periosteum group was faster than that of the control group. Conclusion Imaging can play important role in the research of bone and tendon healing nodes.

Objective To investigate the correlation between the expression of IL-1, IL-6 and IL-17 and bone-tendon junction injury. Methods Thirty-six adult New Zealand rabbits were selected as experimental subjects. Samples were taken 2, 4, 8 weeks after operation for histological detection and double antibody sandwich ABC-ELISA. Results The levels of IL-1, IL-6 and IL-17 increased significantly 2, 4 weeks after operation, compared with before operation (P0.05). The levels of IL-1, IL-6 and IL-17 eight weeks after operation were not significantly dif- ferent from that before operation (P0.05). Conclusion Inflammatory factors (IL-1, IL-6 and IL-17) are closely correlated with bone tendon junction healing.

目的通过对糖尿病足患者进行社区管理,从而提高糖尿病足患者的预防与治疗的效果。方法对比分析法是将经过社区管理的糖尿病足患者与未经过社区管理的糖尿病足患者的检查结果进行比较,从而体现社区管理的有效性。本社康中心共选取了100例患有糖尿病足疾病的患者进行临床观察与分析,将其分为对照组,通过观察社区管理的影响,从而比较其病症治疗结果。结果采用社区管理的50例患者治愈率>60%,相较于比较组患者具有显著优势。结论对糖尿病足患者实施社区管理能够提高患者的饮食质量,培养患者的自我管理能力,改善患者的生活品质,对于糖尿病足患者的发展具有重要的意义。

目的 观察复方雷尼替丁、莫沙比利联合应用治疗胃食管反流病的效果.方法 选择胃食管反流病患者155例,随机分2组:治疗组78例,口服复方雷尼替丁和莫沙比利治疗;对照组77例,口服盐酸雷尼替丁治疗,4周为1疗程.结果 治疗组总有效率为96.2%,对照组总有效率为84.4%,2组总有效率比较,差异有统计学意义(χ2=6.11,P＜0.05).结论 复方雷尼替丁与莫沙比利联合应用治疗胃食管反流病有效率明显高于单独使用盐酸雷尼替丁.