Objective Toobserve theeffects andsideeffectsofpostoperative analgesiaby propacetamolcombined with flurbiprofen axetil and sufentanyl on burned patients undergoing burn wound excision and skin grafting.Me-thods 60 cases were randomly divided into 3 group,with 20 cases in each group.In group A,the load dose of suf-entanyl was 5 g,and for the pump,there were sufentanyl(150 g)+0.9% sodium chloride solution diluting to 100 ml.In group B,the load dose of flurbiprofen axeti was 50 mg,and flurbiprofen axeti 100 mg+sufentanyl 100 g+0.9% sodium chloride solution diluting to 100 ml were infused.In Group C,15 minutes before completing operationi,ntra-venous dripping 2 g of propacetamol were performanced(with 100 ml of sodium chloride solution,15 min);the the load dose of sflurbiprofen axeti was 50 mg,and flurbiprofen axeti(100 mg)+sufentanyl(100 g)+0.9% sodium chlor-ide solution diluting to 100 ml were infused.The maintenance dose was 2 ml/h with single load dose of 0.5 ml and lock time of 15 minutes.After operation,the visual analogue scales(VAS) of quiet and activities after 2,6,12,24 and 48 hours were recorded;and the adverse reactions were compared.Results All the results in three groups are sati-sfying.After 2 and 6 hours,the scores of quiet and activities in group C were lower than those of group A and B( 0.05).There were statistical significances among 3 groups in adverse reactions( 0.05).Conclusions After undergoing burn wound excision and skin grafting,it is more more efficiently and security in analgesia by propaceta-mol combined with flurbiprofen axetil and sufentanyl.

目的探讨SLIPA喉罩在甲状腺手术全身麻醉中的应用效果。方法将60例ASAⅠ～Ⅱ级择期行甲状腺手术患者随机分为SLIPA喉罩组(L组)和气管插管组(T组),各30例。观察并记录两组麻醉诱导前(T0)、麻醉诱导后(T1)、置入气管导管(喉罩)时(T2)、手术开始10min(T3)及术毕拔管(喉罩)时(T4)患者心率(HR)、血氧饱和度(SpO2)、收缩压(SBP)和舒张压(DBP),记录人工气道建立成功时、成功后30min及手术结束时的气道压(Pmean)、气道峰压(Ppeak)、呼气末二氧化碳分压(PETCO2)和术后咽喉疼痛的病例数。结果两组T0～T4时点SpO2均为100%,T2～T4时点T组HR、SBP和DBP较L组明显升高,差异均有统计学意义(<0.05)。两组间人工气道建立成功时、成功后30min及手术结束时Pmean、Ppeak及PETCO2差异均无统计学意义(>0.05)。T组有8例出现不同程度的咽喉疼痛或不适,L组无一例出现。结论全身麻醉下SLIPA喉罩通气用于甲状腺手术效果优于气管插管,其对血流动力学影响小,应激反应轻微。