Objective: To investigate the effects of extremely low frequency magnetic fields(ELF-MFs) on oxidative stress,the relation between ELF-MFs and health,and the oxidative stress-related mechanism of the effects of ELF-MFs on organism.Methods: Introduction of ELF-MFs and public exposure,oxidative stress,and oxidative stress-related diseases.Review of the papers focused on the ELF-MF induced oxidative stress including research on cells and animals published in the past few years.Results: ELF-MFs can induce oxidative stress in cells and animals,enhance the production of reactive oxygen species and other free radicals,and change the capability of antioxidant defenses.The extent of oxidative stress was related to tissue and organ,rose with duration of exposure and strength of ELF-MFs.Conclusions: In a certain aspect,the effects of ELF-MFs on organism were shown on the stimulation of oxidative stress.Further research on the molecular mechanism of the ELF-MF inducing oxidative stress,characteristic of cell injuries,and the relation between ELF-MFs and oxidative stress-related diseases will disclose the effects of ELF-MFs on human health.

近年来,随着国家药监部门对<药品生产质量管理规范>(GMP)推行的日益重视和对GMP认证要求的日益严格,如何把握GMP精神、明确GMP的脉络对各医药企业提出了挑战.本文将GMP各项要求进行了高度概括和总结,将其概括为两个目的 ,即"1.防止污染与交叉污染,2.防止差错与混淆";并总结出GMP管理的两个特性,即"操作前有依据,操作后可追溯".抓住这四点核心思想,有助于在GMP工作中灵活变通,事半功倍.

某高炮的轴角控制信号采用无线方式传输,为了接收数字化的轴角信号,以单片机为基础,采用天线、寄存器芯片等模块设计了无线接收机系统.分析系统的主要组成部件信号转换单元、功率放大器和数字-自整角机转换器的结构、特点及工作原理.

A sort of impact resistant micro-acceleration sensor based on SOI was designed, which solved the problem of insulation leakage when piezoresistive MEMS-accelerometer sensor work in high temperature, this enlarged range of the circumstance temperature effectively. Blue print make craft work to carry out by applying advanced technique such as LIGA, ICP. This research provides guide line for manufacture of high-level piezoresistive sensor in the future.

以本实验室培育的抗白粉病品系"百农3217×Mardler"BC5F4为材料,构建了一个白粉病菌诱导的抑制差减杂交cDNA文库.建库过程质量分析表明,差减杂交效率较高,文库质量较好.文库滴度为4.2×109cfu@ml-1;插入片段平均为300 bp左右.挑取文库阳性克隆960个,扩增插入片段,将其制备成高密度杂交点阵膜.通过探针杂交检测表明,本研究制备点阵膜的方法简便可靠,获得的点阵膜可用于抗病相关基因的筛选研究.

目的探讨抗乙肝特异性转移因子的研制方法及其在临床上疗效的测定.结果治疗组HBeAg阴转率为50%,HBVDNA阴转率为28.57%,对照组HBeAg阴转率为25%,HBVDNA阴转率为0;治疗组CD4/CD8复常率为62.5%,对照组为23%.本实验临床观察,治疗组CD4/CD8复常率明显高于对照组.结论抗乙肝特异性转移因子口服液除直接中和病毒外,还可使人体T细胞增殖转化,通过免疫调整作用达到清除乙肝病毒,提高病毒标志阴转率及T细胞亚群功能的恢复.