In the information age, knowledge and information have become the leading force. Many disciplines are based on information science studied. Some subjects should be the requirements of the times, the realization of cross disciplines, with the rise of some edge science. Hospital scientific research field to realize the innovation, also established the intelligent management system. This article carries on the discussion to the point of scientiifc research at present hospital management.

目的 探讨预防眼底荧光造影不良反应的护理干预方法.方法 将800例眼底荧光造影患者按先后顺序分为对照组和观察组,对照组按常规进行眼底荧光造影,观察纽在对照纽的基础上针对造影中有可能出现的不良反应,包括恶心、呕吐、荨麻疹,青光眼等实施护理干预,具体措施:①心理护理;②造影前的充分准备;③造影过程中的指导.结果 观察组的不良反应的发生率显著低于对照组(均p<0.01).结论 护理干预能有效预防和减少眼底荧光造影不良反应的发生,使患者能够安全顺利地完成检查.

Objective In order to bring data for prevention and treatment in ischemic stroke,Changes of the fun- dus and carotids by color Doppler ultrasonograpby were studied.Methods 110 patients with ischemic stroke were exam- ined with the fundus and color Dopple ultrasonngrapby.Results Hypertensive retinopathy(61.8%)and diabetic reti- nopathy(25.5%)were dominant in all patients.The abnormal rate was 84.5% in carotids by color Doppler ultrasonngra- pby.Conclusion It was helpful to evaluate the atherothrombotic changes when the examinations of fundus and carotids by color Doppler ultrasonograpby were combined.It is also providing objective data in preventing visual impairment that the early diagnosis of the changes of the fundus.

目的:探讨Vogt-小柳原田病的临床表现、眼底荧光血管造影特点和糖皮质激素治疗效果。方法:回顾性分析30例(58眼)Vogt-小柳原田病的临床表现、眼底荧光血管造影的特点和糖皮质激素治疗的效果。结果:所有Vogt-小柳原田病的患者均表现视力下降、视网膜水肿,部分患者出现眼外症状,眼底荧光血管造影有独特的表现,糖皮质激素治疗后,视力均明显提高(P<0.05)。结论:眼底荧光血管造影检查和糖皮质激素的早期合理应用对Vogt-小柳原田病的诊断及预后具有很重要的作用。

Objective:In order to find the characteristic of ocular symptom in ischemic stroke of the aged,the changes of vision,visual field and fundus in 45 patients were analysed. Methods:The examination of vision,visual Field and fundus was carefully recorded. Results:Ischemic stroke of posterior circulation(64.4%) was dominant in all patients. The rate of visual impairment was 69.7% and visual field defects were in oculus unitas,HR、SMD and DR were 63.6%、40.9% and 27.2% respectively in the changes of fundus. Conclusion:The cause of the visual impairment was the changes of fundus,but not ischemic stroke. It is suggested that for the patients with ocular symptom,especially those with normalilty of visual acuity,a close observation including examination of ophthalmology should be made. It was significant value for the prevention,treatment and prognosis that the ocular changes could be discovered earlily.

Objective To improve diagnoses and treatment of painful ophthalmoplegia syndrome and study possible etiology of the syndrome.Methods Eighteen cases with painful ophthalmoplegia syndrome diagnosed clinically were collected and their modes of onset,the involvement of the cranial nerves and the results of the special examinations were analyzed.Results The syndrome of multiple cranial nerves with ophthalmopathy were found.Cerebrospinal fluid and neuroimaging examinations may be abnormal.Conclusion The patients with headache or sigle ophthalmoplegia must be diagnosed with exclusion.Possible etiology of the syndrome is nonspecific inflammatory with immune reaction,besides,satisfactory effect of adrenocorticotrophic hormone is acquired after corticosteroid treatment has no effect.

Aim: To investigate the clinical features of nonarteritic anterior ischemic optic neuropathy (NAION). Methods: Clinical data of 72 patients (80 eyes) with NAION in the Department of Ophthalmology, Second Affiliated Hospital of Guangzhou Medical College during January 2000 to January 2003, 39 males (44 eyes) and 33 females (36 eyes), were analyzed. Among them, 64 patients had ocellus disease (89%) and 8 patients with oculus uterque (11%). Exclusive criteria: All the patients had no symptoms of giant cell arteritis. Inclusive criteria: ill history, symptom, fundus, visual field and fluorescence fundus angiography (FFA) results were all in accordance with diagnosis criteria of NAION. Clinical data of 72 patients (80 eyes) who had been diagnosed to have anterior ischemic optic neuropathy by view, visual field, fundus and FFA were analyzed. Results: Of the 72 patients, 28 (30 eyes) were accompanied with hypertension arteriosclerosis, 20(24 eyes) accompanied with diabetes, 14 (15 eyes) accompanied with hyperlipemia, 4(5 eyes) accompanied with glaucoma, 2 (2 eyes) were accompanied with post-operation cataract and 4 (4 eyes) had unknown reasons. Fundus papilloedema showed light color, among them, 21 eyes were quadrant edema, 19 eyes showed edema of half optic disc, 28 had edema of all optic disc, and 12 had no edema. At the early stage of FFA, all optic disc or parts of fluorescence filling were delayed or defected, and showed the defect positions and ranges. At the later stage, fluorescence filling was various; the defect positions were stronger or weaker fluorescent light, mainly the stronger, including 68 eyes(85%), with shorter courses. Otherwise, the continuous weaker was often seen in the longer course, including 12 eyes (15%). The ischemic sites and ranges in 60 eyes (75%) showed by FFA had visual defects correspondingly. Conclusion: NAION is a ophthalmocace caused by multiple factors, and the dominant factors are hypertension, artery sclerosis of retina, diabetics and hyperlipemia. Ischemic sites and corresponding visual defect detected by FFA are main diagnostic evidences of this disease.

Objective:To investigate the blood supply of optic disc in primary open angle glaucoma (POAG) by fundus fluorescein angiography (FFA). Methods:The results of FFA from 63 cases of POAG were analyzed,in which the influence of the High blood pressure,diabetes and other system disease was excluded. Results:On FFA,low or part filling of fluorescence was shown in all 63 cases, lasting low fuorescence at terminal time in 15 cases,23 cases without fluorescein filling equably,thick fluorescein filling in 24 cases,and fluorescein leakage at rim or bottom of the disc in 63 cases.17 cases revealed more than 15 seconds arm-retina circulation time,which was obvious in superotemporal and inferotemporal sides.There were 9 cases that had retinal bleeding and fluorescein cover at rim,and 8 cases wither around disc.In 5 cases the C/D difference between two eyes was more than 0.2. Conclusions:FFA is an important way to evaluate the blood provision of the disc in glaucoma.

摘要:目的:观察高度近视性黄斑出血的临床特点和探讨其治疗方法.方法:对确诊为高度近视性黄班出血的28例32眼分别作视力、矫正视力、眼前节、眼底、A/B超、眼底彩照和眼底荧光血管造影(fundus fluorecein angiography,FFA)等检查,给予中西药物治疗,随访观察2～26个月(平均16个月).结果:经FFA检查32眼中28眼(87.5%)为单纯型黄斑出血,其中25眼(89.3%)伴有漆裂样纹.出血经治疗多在15天至2个月吸收;另外4眼FFA显示为脉络膜新生血管出血,最终均因反复出血,后巩膜葡萄肿和脉络膜萎缩而预后较差.结论:高度近视性黄斑出血分单纯型和脉络膜新生血管型,前者出血吸收快,后者反复出血严重损害中心视力而预后不良.

目的通过分析73例临床确诊多发性硬化(multiple sc lerosis,MS)患者的视力、视野、视觉诱发电位(visual evoked potential,VEP)改变,以找出MS侵犯视路的特点.方法视力减退者常规行视力、视野检查,全部患者均行VEP检查.结果本组患者中视力减退率为39.7%,视野缺损呈复杂多变,MS伴脊髓病变者有84.2%VEP异常,显著高于无脊髓病变的MS患者.结论 MS易侵犯视路,建议对视功能障碍者,尤其是复发性视力障碍,且视野缺损呈复杂多变者,在全面观察的基础上应注意是否有脊髓病变,以警惕MS的存在,同时行VEP检查,不仅可以发现MS亚临床病灶,动态随访观察,还可以客观评价疗效与预后.