Objective To investigate the situation of knowledge,attitude and practice about hepatitis B of undergraduates in Guangzhou,and then provide basis for health education.Method 700 undergraduates from 4 universities in Guangzhou were investigated with the same questionnaires of KAP about hepatitis B.Results On the knowledge,57.7% had learned that the main infection source of HBV was the patients and the HBV-carriers.Only 22.9% had learned how to explain the result of test of HBV.The medical undergraduates' knowledge were more superior to the non-medical ones(P0.01).On the attitude,30.7% worried to get the hepatitis B.The male and the country undergraduates could accepted a HBV carrier lover,it was more enlightened than the female and the town undergraduates(P0.01).On the practice,the females had done better than the males(P0.01).The non-medical undergraduates drank more frequently than the medical ones and they did worse on the hands washing(P0.01).The town students did better than the county students on the behavior of hands washing and vaccination(P0.01).Through the Pearson's analysis,three dimensionalities of knowledge,attitude and practice were positive correlative.Conclusion Health education should be taken according to different points for the different students,and during the education,it is necessary to highlight the using of network.