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1 病例资料病史:患者男性,60岁,因"双下肢麻木、疼痛、活动不利3月余"于2004年7月8日人院.患者2003年9月份体检时发现"糖尿病",住院治疗后发现血白细胞总数升高,经进一步检查确诊为"急性淋巴细胞性白血病",住血液科行定期化疗,至今已6个疗程.

2007CHINESE JOURNAL OF REHABILITATION MEDICINE（2007）

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2电刺激小脑顶核在失眠治疗中的应用

厉苏苏

目的观察电刺激小脑顶核对失眠的疗效。方法选择南京医科大学第一附属医院2004-05/2005-03收治的失眠患者15例,应用脑循环功能治疗仪电刺激小脑顶核,将两个电极置于耳后乳突处,模式:1;比率1∶2;频率136Hz,时间20～30min,治疗强度:耐受量。1次/d,10次为1个疗程,治疗2个疗程。治疗前和治疗1个月后评估疗效(痊愈:症状消失,睡眠>6h;显效:睡眠4.0～5.0h;好转:症状减轻,睡眠有所改善;)。结果15例全部进入结果分析。治疗后痊愈2例,显效6例,好转4例,无效3例。结论电刺激小脑顶核对失眠有显著疗效,可延长睡眠时间,使入睡容易。

2006Chinese Journal of Clinical Rehabilitation（2006）引用：3

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3Effects of 3-Phase Rehabilitation on Functional Outcome in Hemiplegia after Stroke

侯红,王彤,王红星,厉苏苏

Objective:To explore the effects of 3-phase rehabilitation on functional outcome in patients with hemiplegia after stroke. Method: 80 hemiplegia patients were randomly divided into rehabilitation group and control group. The patients in control group only received medication treatment,and the patients in rehabilitation group were given regularly physical training except medication. Motor function and the ability of daily activities (Barthel Index) were compared pre-treatment and 1mon,3mon,6mon post-treatment.Result:①The motor function of upper extremities,hand and lower extremities had no significant difference between two groups(P0.05).After 1mon rehabilitation,motor function of upper and lower extremities in rehabilitation group improved significantly than control group(P0.05),and more significantly after 3 and 6 months training(P0.01). The motor function of hand in rehabilitation group had significant difference compared with the control group after 6mon training.② ADL had no difference between two groups pre-treatment.After 1mon training,ADL in rehabilitation group improved significantly than control group(P0.05).After 3-6mon rehabilitation,the difference was more significant(P0.01). Conclusion:3-phase rehabilitation can improve effectively the motor function of extremities and ADL of hemiplegia patients after stroke and reduce rate of complication.

2006CHINESE JOURNAL OF REHABILITATION MEDICINE（2006）引用：34

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4氦-氖激光治疗颞颌关节紊乱综合征的疗效观察

厉苏苏,蔡可书

颞颌关节紊乱综合征是口腔颌面部常见疾病之一,大多数学者认为其病因为精神因素、咬合因素、不良习惯、创伤等多种因素共同作用的结果,我们应用氦-氖激光照射疗法治疗颞颌关节紊乱综合征36例(39侧),经过临床观察,效果良好,现报告如下.

2004CHINESE JOURNAL OF REHABILITATION MEDICINE（2004）

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5Experimental Study of the Effect of He-Ne Laser Irradiation on Injured Brain Injuries in Rats

王彤,王红星,厉苏苏,陆晓,王蓓蓓,侯红,宋凡

目的采用He-Ne激光直接照射大鼠颅骨缺损部位的脑组织,观察He-Ne激光对脑损伤早期组织形态学、代谢、功能的影响.方法 66只Wistar大鼠随机分为A、B、C、D、E、F六组,均在麻醉下去除部分颅骨制作脑损伤模型.采用波长为632.8 nm,输出功率25 mW的He-Ne激光照射脑组织,光斑直径2 cm,照射距离70 cm.A、B、C为即刻观察组;E、F为1周观察组.取损伤侧脑组织和血浆分别测定损伤侧脑组织及血浆中丙二醛(MDA)的含量和超氧化物岐化酶(SOD)的活性;光镜观察脑组织形态学变化;评定1周观察组大鼠处理前后平衡及支撑时间的改变.结果即刻观察组中各激光照射组与对照组形态观察未见明显差异;经组间配对t检验发现,A、B、C组与D组之间进行比较血浆中MDA值明显降低(P=0.000) ,血浆中SOD值无显著性差异;1周观察组中治疗组血浆MDA值较对照组明显减少(P=0.001),SOD值较对照组明显增高(P=0.001),治疗组损伤侧脑组织中MDA值也明显低于对照组(P=0.001),大鼠平衡时间(P=0.02)和支撑时间(P=0.0016)较对照组有明显提高.结论不同剂量He-Ne激光的即刻照射对大鼠脑组织的形态学改变、脑组织中的MDA/SOD和血浆中的SOD改变影响不大;1周He-Ne激光直接照射可降低脑损伤大鼠血浆和脑组织MDA含量,增强血浆中SOD的活性,改善肢体平衡和支撑功能.

2002引用：1

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