目的 分析北京市海淀区一起腺病毒53型引起的结膜炎暴发疫情流行病学特征.方法 对某中学发生的结膜炎病例进行流行病学调查,采集咽拭子和眼拭子标本进行病毒分离和鉴定.结果 病例主要集中在初一、初二和初三年级,患病率分别为11.5％、14.9％和9.8％,流行曲线为单峰分布,疫情持续59 d,由学生通过密切接触传播.平均年龄14.4岁.患者以眼部不适症状为主,无发热症状,其中单眼不适61例,占85.9％;双眼不适10例,占14.1％.其中结膜充血41例,占57.7％;畏光1例,占1.4％;眼部疼痛5例,占7.0％;眼痒7例,占9.9％;眼分泌物增多3例,占4.2％.推测最长潜伏期为35 d.经过Hep-2细胞培养分离毒株4株,采用中和试验鉴定为腺病毒53型,与PCR检测结果一致.结论 该起疫情是由腺病毒53型引起的结膜炎暴发,应加强对高危人群防控知识的宣传教育.

Objective To understand the epidemiological characteristics of viral diarrhea among adults in Haidian district, Beijing.Methods Stool samples were collected from 282 adults in Haidian district of Beijing from June 2012 to May 2013 to detect five kinds of common diarrhea virus with fluorescent PCR. Results 119 samples were detected among 282(42.20%, 119/282), the detection rate was 9.22% for rotavirus, 26.60% for norovirus, 5.32% for astrovirus, 2.84% for sapovirus and 0.00% for adenovirus.Co-infection was detected in 5 cases. The most common type was co-infection of sapovirus and norovirus, accounting for 60.00%(3/5). Adults of 20-40 years old were the major patients, the incidence peaks of viral diarrhea among adults occurred in autumn and winter. Conclusion Norovirus is the most prevalent pathogen of adults viral diarrhea in Haidian district of Beijing in 2012-2013,followed by rotavirus. Co-infection is detected too, to which close attention should be paid in future epidemiological and etiological researches.