目的:研究针对早期慢性乙型病毒性肝炎肝硬化应用彩色多普勒超声半定量评分的价值.方法:随机抽取在2017年12月底到2019年1月初期间通过我院组织安排的肝组织活检确认患有慢性乙型病毒性肝炎的100名患者,根据实际检查结果 分为早期肝硬化组30名以及非肝硬化组70名,检查结果采用彩色多普勒超声进行检查.结果:早期肝硬化组患者的各项彩色多普勒超声各参数半定量评分相比于非肝硬化组要高的多(P<0.05);非肝硬化组的门静脉内径、流速以及流量均要显著低于早期肝硬化组(P<0.05).结论:彩色多普勒超声半定量评分在对早期慢性乙型病毒性肝炎肝硬化的临床诊断中有着良好的诊断应用效果,值得在临床诊断中大力推广.

目的:探究经动脉介入联合超声下射频消融治疗肝脏恶性肿瘤的临床效果评价.方法:此次研究选取的研究对象为肝脏恶性肿瘤患者80例,根据治疗方式不同进行分组,分别为对照组与实验组各40例,给予对照组经动脉介入治疗,给予实验组经动脉介入联合超声下射频消融治疗.对比两组患者的甲胎蛋白与治疗效果.结果:比对两组患者治疗后的甲胎蛋白水平,实验组改善优于对照组,组间差异呈P<0.05,统计学意义存在.比对两组患者治疗后的治疗有效率,实验组优于对照组,组间差异呈P<0.05,统计学意义存在.结论:肝脏恶性肿瘤应用经动脉介入联合超声下射频消融治疗,有效改善甲胎蛋白水平,提高治疗有效率,治疗效果显著.

目的探讨超声造影检查在小肝癌诊断中的应用及其影像表现特点。方法选取2013年6月~2015年6月我院收治的小肝癌患者67例，作为研究对象。所有患者均经穿刺病理活检证实为早期肝癌，对所有患者行超声造影检查，并依据超声影像几灌注特征进行诊断，研究其超声影像特征以及与病理表现的相关性。结果67例小肝癌患者经超声造影检查确诊64例，确诊率为95.52%，与病理证实结果比较无显著差异，>0.05，不具有统计学意义；超声造影三时相观察可知，小肝癌动脉期早期快速增强，动脉期中晚期以及门静脉早期呈快退表现；不同分化程度小肝癌超声造影增强时间、达峰时间比较无显著差异，但不同分化程度的小肝癌廓清时间比较存在显著差异，其中以高分化者开始廓清时间晚于低分化者。结论采用超声造影检查可有效提高临床小肝癌诊断及病情评估能力，对不同病理分化程度小肝癌评价准确，无创性检查适用于中老年小肝癌患者的动态病情监测。

目的：探讨彩超引导经皮经肝胆囊穿刺置管引流术治疗老年急性化脓性胆囊炎的临床疗效。方法选取2012年1月~2015年6月我院收治的老年急性化脓性胆囊炎患者86例,作为研究对象。采用随机数表法将所有患者分为观察组与对照组,每组患者43例,其中对照组患者行常规胆囊切除术,观察组患者在彩超引导下行经皮经肝胆囊穿刺置管引流术,比较两组患者胃肠减压时间、抗生素应用时间、导管留置时间、住院时间以及并发症发生情况等。结果本组实验86例患者治疗后均无死亡发生,观察组患者治疗后胃肠减压时间、抗生素应用时间、治疗费用、住院时间明显短于对照组,<0.05,差异具有统计学意义；观察组治疗后发生1例并发症,发生率为2.33%,对照组术后发生并发症17例,发生率为39.53%,观察组患者术后并发症发生率明显低于对照组,<0.05,差异具有统计学意义。结论采用超声引导经皮经肝胆囊穿刺置管引流术治疗老年急性化脓性胆囊炎疗效确切,可有效缩短患者胃肠减压时间、住院时间等,并且不良反应发生率较低,治疗安全性较高,治疗费用相对较低。

Objective To investigate the incidence and possible related factors for fatty liver among workers engaged in light manual labor in Tianjin, China. Methods Among 800 healthy workers engaged in light manual labor randomly selected from a company in Tianjin, a total of 602 healthy workers completed physical examination and data collection. The content of fat and liver stiffness were determined by controlled attenuation parameter (CAP) using FibroScan, and the disease history, body mass, height, blood pressure, and living habits in all subjects were investigated. The possible related factors for different degrees of fatty liver were analyzed. Between-group comparison of continuous data was performed using the Kruskal-Wallis H test, and comparison of categorical data was performed using χ2 test with row×column tables. Pairwise comparison was performed using χ2 segmentation method, and the agreement between CAP and color ultrasound was analyzed using the Kappa coefficient. Results Among the 602 subjects, there were 180 (29.9%), 195 (32.3%), and 227 (37.7%) subjects with severe fatty liver, moderate fatty liver, and no fatty liver, respectively. There were significant differences in age, body mass index, waist-hip ratio, smoking, drinking, history of diabetes, and family history between the above three groups according to CAP (P＜0.05 for all). With higher sensitivity, CAP achieved a significantly higher detection rate of fatty liver than traditional color ultrasound (62.3% vs 44.0%, P=0.000). The agreement between two methods was poor (Kappa value ＜0.4). Conclusion Among the so-called “healthy people” engaged in light manual labor, the incidence of fatty liver has exceeded 60%, which is associated with body mass index, waist-hip ratio, bad living habits, history of diabetes, and family history of fatty liver. CAP can noninvasively detect fatty liver with higher sensitivity and less time; however, its clinical significance needs further studies.