Objective To evaluate the clinical effect and value of CT-guided percutaneous microwave abla-tion therapy for lung cancer. Methods From October 2014 to December 2016, the clinical data of 60 patients with peripheral lung cancer were analyzed, and they were randomly divided into the chemotherapy group and the micro-wave ablation group, 30 cases in each group. The chemotherapy group was given GP chemotherapy, and the micro-wave ablation group was given CT-guided percutaneous microwave ablation therapy. Their clinical efficacy was com-pared. Results Karnofsky score showed no significant difference between the two groups before treatment ( P >0. 05). After treatment, the total effective rate was obviously higher in the microwave ablation group (60. 0%) than in the chemotherapy group (33. 3%) (P<0. 05). 1 and 3 months after treatment, Karnofsky score was significantly higher in the microwave ablation group than in the chemotherapy group ( P<0. 05 ) . The incidence of adverse reac-tions was 16. 7% in the microwave ablation, significantly lower than 40% in the chemotherapy group ( P<0. 05 ) . Conclusion Compared with chemotherapy alone, the use of CT-guided percutaneous microwave ablation has better curative effect, less invasive effect and higher safety.
Objective To explore the influencing factors and long-term efficacy of transcatheter arterial chemoemboliza-tion( TACE) combined with microwave ablation therapy ( MWA) for advanced liver cancer.Methods 90 patients with advanced primary liver cancer who underwent TACE combined with MWA were followed up ,1~5 years survival rates were analyzed.7 fac-tors affecting long-term curative effects of TACE combined with MWA were studied by single factor variance analysis ,the statisti-cal difference was screened and analyzed by logistic regression analysis ,the independent influencing factors were examined.Re-sults Of 88 patients,there had 82 cases of death,accounting for 93.18% in follow-uPcases.1-,2-,3-,4-,5-year survival rates were 73.86%,45.45%,32.95%,25%,13.63%.Single factor variance analysis showed that clinical grading ,Child-Pugh grad-ing,tumor diameter,portal vein tumor thrombus and targeted drug therapy were factors affecting 3-year survival rate of liver cancer patients treated with TACE combined with MWA ,these 5 factors were studied by logistic regression analysis ,the results showed that clinical grading ,tumor diameter ,portal vein tumor thrombus and targeted drug therapy independent influence factor for 3-year survival rate of liver cancer patients treated with TACE combined with MWA.Conclusion Targeted drug therapy is independent protective factor for liver cancer patients treated with TACE combined with MWA ,clinical grading,tumor diameter,portal vein tumor thrombus are independent risk factors.