Objective:To investigate application of psychological suggestion in the tooth extraction of collegians. Methods:One hundred and eighteen college students who received tooth extraction from 2008.1 to 2012.12 were randomly divided into two groups, which were psychological suggestion group and control group. Each group has 59 cases. The psychological sugges-tion group were received psychological suggestion treatment before the extraction of teeth, and the controlled group were not giv-en any suggestion. It was conducted according to the statistical data from the three ranks which are cool-headed type, dismay type and mixed type. Results:The rate of cool-headed type in the group of psychological suggestion is obviously higher than that of control group (P<0.01) ; and dismay type leads obviously to be lower than that of control group (P>0.05) . Conclu-sions:The application of psychological suggestion in the tooth extraction can effectively help collegians relieve stress and fear, avoid unnecessary worries, shorten operative time, put an end to the accident, and to ensure the smoothness of operations.