目的 观察青光眼睫状体炎综合征反复发作是否会对视网膜神经纤维层厚度及视野产生影响.方法 收集2014年7月—2016年7月在我院诊断为青光眼睫状体炎综合征且发作2次的患者16例,将其发病眼作为发作眼组,对侧眼列为对侧眼组,选取在我院健康体检者为正常对照组.在第1次及第2次发作眼压控制后3 d内及满3个月时均记录一般资料、眼部常规检查,并运用自动视野计行标准全视野检查,眼科相干光断层扫描仪行以视乳头为中心1.73 mm半径内不同象限视网膜神经纤维层厚度检查.结果 各组不同时间点视网膜神经纤维层厚度的比较差异无统计学意义(P>0.05);16例患者在反复发作后出现视野缺损和出现鼻侧阶梯或者旁中心暗点的患者均为0例(0眼).结论 青光眼睫状体炎综合征反复发作对视网膜神经纤维层厚度的改变不明显,但可能出现视野损害.

目的:探讨舌下脱敏治疗对过敏性结膜炎的效果.方法:将62例尘螨过敏性结膜炎患者按就诊日期单双号分为对症治疗组与脱敏治疗组,每组各31例,疗程均为24个月.对症治疗组发作期滴用抗组胺眼液,严重者口服抗组胺药物;脱敏治疗组舌下含服粉尘螨滴剂脱敏治疗,治疗过程有临床症状重者短期加用滴用抗组胺眼液.对比两组治疗效果.结果:治疗后两组症状和体征评分比较,差异均有统计学意义(P<0.05).治疗前两组对症用药评分比较,差异无统计学意义(P=0.19);治疗后两组对症用药评分比较差异有统计学意义(P<0.05).脱敏治疗组治疗前与治疗后的对症用药评分比较,差异有统计学意义(P<0.05),对症治疗组治疗后用药评分明显下降.对症治疗组治愈1例(3.2%),显效8例(25.8%),有效16例(51.6%),无效6例(19.4%),总有效率29.0%;脱敏治疗组治愈12例(38.7%),显效11例(35.5%),有效5例(16.1%),无效3例(9.7%),总有效率74.2%,两组比较差异有统计学意义(P<0.05).结论:舌下含服粉尘螨滴剂治疗过敏性结膜炎疗效显著,治愈率高.

Background: The aim of this study is to provide a quantitative evaluation of the blood-aqueous barrier (BAB) in patients with ocular blunt trauma and evaluate its association with intraocular pressure (IOP) elevation. Methods: This is a prospective case-control study, and the following 3 groups were included: elevated IOP (45 patients with an elevated IOP secondary to ocular blunt trauma), normal IOP (27 patients with a normal IOP after ocular blunt trauma), and healthy controls. The main outcome measures were IOP and BAB function evaluated using a laser flare-cell meter (LFCM). Results: Patients had significantly higher flare intensities and cell counts than the normal controls (both p < 0.001), and the elevated-IOP group displayed even higher LFCM readings than the normal-IOP group. Aqueous flare and cell readings were positively correlated with IOP (r = 0.529 and 0.590, respectively, p < 0.001). LFCM readings in the elevated-IOP group were still significantly high even on postraumatic day 120 following anti-inflammatory treatment. Conclusion: BAB dysfunction occurred following ocular blunt trauma. Eyes with an elevated IOP displayed a more seriously disturbed BAB and a longer recovery course. Examination with a LFCM provides insight into the pathophysiology of IOP elevation and assists in making decisions concerning anti-inflammatory treatment during follow-up.

Objective To observe the changes in retinal nerve fiber layer thickness in patients diagnosed with Pos -ner-Schlossman’s Syndrome.Methods Twenty-eight patients with Posner-Schlossman’s Syndrome and 30 normal sub-jects were included in our study .Bilateral retinal nerve fiber layer thickness ( RNFLT) were measured using optical coher-ence tomography ( OCT) within 3 days and 3 months after the attack .Results There was no significant difference in the changes of RNFLT among all the groups mentioned above .Conclusions There was no visual function loss after PSS attack in term.PSS may still be considered as having a good prognosis .

Objective Through comparising clinical test indexes of dry eye in aged pantients with Sjogren Syndrome and normal aged people to explore the better diagnosis indexes for dry eye pantients with Sjogren Syndrome among the elderly.Methods Twenty-eight patints(56 eyes) aged over 60 with dry eye associated with Sjogren Syndrome were collected as SS group, and another thirty-two normal people also aged over 60 were collected as normal control group. They were all examined with SchirmerⅠtest(SⅠt), lfuorescein staining, (FL)and the iflm break-up time(BUT). The indexes between the two groups were analyzed.Results There was no signiifcant difference between them in SⅠt and BUT, while there was signiifcant difference between them in FL. Conclusion FL maybe an important indexes for evaluation the state of dry eye in aged people with Sjogren Syndrome.

【Objective】 To observe the recovery of BAB function in patients suffering from secondary glaucoma in early stage ocular contusion and the efficacy of medication therapy.【Methods】 Sixty-one patients of ocular contusion in early stage were enrolled,and 30 healthy persons were collected as the control.Patients were divided into normal intraocular pressure group(NIOP) and high intraocular group(HIOP).Treatments included cortical steroids and/or NASIDs treatments in all patients and antiglaumatous medications in HIOP group.LFCM was tested in the first week and on day 14,30,60,90,and 120 after ocular trauma.The correlation of IOP with flare level and cells number in aqueous humor was analyzed.【Results】 The results of flare values and cell counts were positively correlated with the IOP of all patients(r = 0.529 and 0.590 respectively,P 0.001).Before the treatment,both the flare level reading and the cells number reading in HIOP group [(78 ± 60)pc/ms,(205 ± 88) cells/0.5 mm3] were significantly higher than those in NIOP group [(20 ± 16) pc/ms,(50 ± 16) cells/0.5 mm3].Flare level and cells number of all patients decreased gradually.In NIOP group,the LFCM readings [(5 ± 2) pc/ms,(1 ± 1) cells/0.5 mm3] were back to normal in 30 days while the readings in HIOP group [(9 ± 1) pc/ms,(5 ± 3) cells/0.5 mm3] were still a little higher in 120 days.Pre-treatment and post-treatment IOP of HIOP group were(39 ± 10) mmHg and(19 ± 11)mmHg,and the IOP level was significantly lowered(P = 0.001).Thirty-one patients in HIOP group(79.5%) had IOP controlled without further operations.【Conclusions】 LFCM readings increase after ocular contusion especially in HIOP patients,and IOP is positively correlative with BAB impairment.The curative rate of medication for traumatic glaucoma in early stage could be 79.5%.Administration of cortical steroid and NSAIDs is effective in enhancing BAB recovery and is helpful to control the IOP.

Objective To investigate the effect of trabeculectomy combined with segmental iridectomy, mitomycin C (MMC) and viscoelastic agents usage on the treatment of glaucoma secondary in uveitis. Methods According to the age, degree of inflammation and the condition of Tenon capsule of patients, differ-ent concentration of MMC (0.25-0.33 mg/ml) was used during the operation, with separation of the anterior and posterior synechia, resection of pupillary organization membrane using viscoelastic agents. Segmental iridec-tomy and releasable sutures were also performed on the patients. The visual acuity of preoperation and postoper-ation, intraocular pressure, inflammation and the complication were record. Results Forty-two eyes of 38 cases with glaucoma secondary in uveitis were studied, the mean follow-up time was (12.01±3.56) months. The postoperative visual acuity improved in 14 eyes, didn't change in 28 eyes. The postoperative inflammation of anterior chamber disappeared in 35 eyes, relieved in 7 eyes. And the average postoperative intraocular pres-sure (15.20± 4.64) mmHg was significantly lower than the preoperative intraocular pressure (38.37±12.93) mmHg (t = 8.255, P = 0.000). The total success rate was 92.9%. There were no severe complication. Conclusion Trabeculeetomy combined with MMC, viscoelastic agents usage, separation of anterior and poste-rior syneehia, segmental iridectomy and releasable suture could increase the success rate of operation on pa tients with glaucoma secondary in uveitis, decrease the complication and inflammation reaction of operation, and the recurrence of uveitis.