OBJECTIVE:To investigate the clinical manifestations and diagnostic method of hyperparathyroidism due to parathyroid tumors and to evaluate the intra-operative detection of parathyroid hormone in surgical treatment.METHOD:Thirty-seven cases with functional parathyroid tumors from January 2003 to October 2012 were retrospectively analyzed. The clinical manifestation, examination and operation method, changes of parathyroid hormone before and after operation were collected.RESULT:All cases were definitely diagnosed before operation. The sensitivity and the positively predictive values of neck ultrasonography were 86.5% and 97.6% respectively, and the same data of Tc-99m-MIBI was 97.2% and 100.0%. The PTH levels declined by 84.9% ten minutes after tumor resecting compared with the level before operation. The serum calcium and PTH returned to normal levels and symptomatic relief occurred after operation.CONCLUSION:Recurrent bone disease, long-term urinary calculus and obscure gastrointestinal symptoms were common symptoms of hyperparathyroidism due to parathyroid tumors. The neck ultrasonography and Tc-99m-MIBI were suitable for location of parathyroid tumors. Surgical operation was an effective treatment for parathyroid tumor. Intra-operative PTH assay would be able to ensure the radical excision and the operative safety for functional parathyroid tumors.
目的:总结32例冠状动脉旁路移植术(CABG)术后处理的临床经验,并做进一步探讨.方法:2002年9月~2004年10月,连续观察32例冠状动脉旁路移植术后患者,其中单支病变6例,双支病变15例,三支病变11例,记录心电图、中心静脉压、有创动脉压、电解质、引流量、血气分析等.结果:平均呼吸机辅助时间16±3 5h,呼吸衰竭2例,心律失常10例,低心排出量综合征(LCOS)3例.结论:CABG术后充分供氧、适时、尽早拔管很重要,维持血容量、电解质平衡,注意低心排出量综合征,及时处理各种心律失常.总之,CABG术后全面、精细的处理对顺利恢复至关重要,是手术成功不可缺少的重要保障.