Objective:To assess the interobserver and inter-modalities agreement with two non-invasive diagnostic modalities of hepatocellular carcinoma in high-risk patients: contrast-enhanced ultrasound liver imaging reporting and data system (CEUS LI-RADS) and magnetic resonance imaging liver imaging reporting and data system (MRI LI-RADS).Methods:From August 2017 to August 2019, the CEUS and MRI data of patients at high risk for HCC from the Second Affiliated Hospital of Zhejiang University School of Medicine were analyzed retrospectively. A total of 217 lesions in 173 patients were classified according to CEUS LI-RADS v. 2017 or MRI LI-RADS v. 2018, by 4 blinded independent observers with more than 10 years of experience of CEUS or MRI. Interobserver and inter-modalities agreement was assessed with Cohen′s kappa.Results:The interobserver agreement was moderate and comparable for CEUS/MRI LI-RADS category (κ=0.606/0.603), the inter-modalities agreement was moderate for CEUS and MRI LI-RADS category (κ=0.564), LI-RADS 3, M, 4 and 5 by two imaging methods showed that the Kappa values were 0.739, 0.551, 0.734 and 0.592, respectively.Conclusions:The total inter-modalities agreement between CEUS and MRI LI-RADS categories is moderate, while the agreements of LI-RADS 3, 4 are strong, and LI-RADS M, 5 are moderate.

嗅神经母细胞瘤(esthesioneuroblastoma,ENB)是一种约占鼻腔3％-5％的少见神经上皮源性恶性肿瘤,近年来发现该病并非罕见.ENB主要发病部位与嗅粘膜分布一致,起源于筛骨骨板、鼻中隔上1/3、上鼻甲及前组筛窦粘膜的嗅神经上皮层.值得一提的是,由于异位嗅粘膜的存在,其他鼻窦腔、鼻咽、蝶鞍、鞍旁及嗅沟等亦可发病.本病的男女发病率并无明显差异,且可发生于任何年龄,但存在两个高峰发病期,分别为11-20岁及50-60岁.