Objective:To analyze the value of applying clinical test biochemical indicators in the diagnosis of patients with viral liver disease.Methods:86 patients with viral liver disease admitted to our hospital from April 2020 to March 202 1 were selected as the study group,and 86 healthy patients coming to our hospital for physical examination in the same period were selected as the reference group.Both the study and reference groups were tested for biochemical indicators.To compare the biochemical indicators of the two groups,the positive rate of liver function index.Results:The lymphocyte count,ALT and total bilirubin index levels in the study group were higher than the reference group (P ＜0.05 );the neutrophil count,platelet count,leukocyte count,albumin and white bulb ratio levels were lower than the reference group (P ＜0.05).The positive rate of liver function index in the study group was higher than that in the reference group (P ＜0.05).Conclusion:A number of biochemical indicators can directly reflect the patient''s condition.Compared with healthy people,the biochemical indicators of patients with viral liver disease are obviously abnormal,and clinical biochemical tests is of great significance to the diagnosis of patients.
BACKGROUND:Although there are many studies addressing osteoarthritis in China, population-based epidemiological studies of knee osteoarthritis have been rarely reported. OBJECTIVE:To explore and analyze the clinical efficacy of early ladder-like treatment in knee osteoarthritis patients from Zoucheng city in the southwest of Shandong province based on an epidemiological investigation. METHODS: A total of 3 427 people randomly enroled from Zoucheng city located in the southwest of Shandong province in 2008 were taken as research objects. A self-designed epidemiological survey on knee osteoarthritis was carried out to analyze the sex, age, urban and rural distribution, and incidence of knee osteoarthritis. According to Kelgren Lawrence Grading, 208 patients with levels 0, I, II of knee osteoarthritis were randomly selected and divided into two groups: surgical treatment group was given intraarticular injection, intraarticular rinsing, arthroscopic treatment and functional exercise; oral drug group was only given oral administration of non-steroidal anti-inflammatory drugs and blood circulation drugs. Ninety-eight patients in the surgical treatment group and 87 in the oral drug group were folowed-up for over 1 year. RESULTS AND CONCLUSION:The incidence of knee osteoarthritis showed an increasing trend with aging in Zoucheng city. There were 33.2% patients who did not receive treatment, 53.2% patients who received irregular treatment, and only 13.6 patients who could folow the doctor’s advice. The excelent rate and total effective rate were higher in the surgical treatment group (81% and 99%) than the control group (34% and 87%;P < 0.01). This epidemiological investigation exerts a certain protective role in the occurrence and development of knee osteoarthritis, and active early ladder-like treatment has achieved good outcomes in patients with knee osteoarthritis.
目的：探究胃癌行CA724、CEA、CA242、CA199肿瘤标志物联合检测的价值。方法选择胃癌患者180例作为研究组，同期选择胃溃疡患者30例作为对照组，同期选择浅表性胃炎患者30例作为参照组，均予放射免疫、电化学发光及酶联相关免疫方法检测，分析3组肿瘤标志物（ CA724、CEA、CA242、CA199）水平、胃癌各肿瘤标志物阳性及联合检验特异性和敏感度情况。结果研究组CA724、CEA、CA242、CA199各指标水平明显高于对照组和参照组（P均＜0．05）；研究组分化程度差者、有肝转移者血清各指标阳性率高；临床分期为Ⅰ～Ⅱ期血清各指标阳性率明显比Ⅲ期和Ⅳ期低（P均＜0．05）；Ⅲ期和Ⅳ期各指标阳性率比较差异无统计学意义（P＞0．05）。研究组4项联合检测相比单项、2项和3项检测敏感度高（ P均＜0．05）。结论对胃癌予CA724、CEA、CA242、CA199肿瘤标志物联合检测，能有效提升胃癌检出特异性和敏感度，利于该病早期诊断和治疗，具一定临床应用和研究价值。
目的:探讨成人败血症病原菌感染的危险因素,菌群分布和防治措施。方法:回顾分析1997年10月-2003年10月经血培养和临床资料证实的51例成人败血症。结果:51例败血症,院内感染占45.1%,院外感染54.9%;有基础病因和夹杂病患者占74.5%;致病菌分布特点:有G+菌上升、G-菌下降的趋势,但仍以G-菌为主。结论:积极治疗原发病和慢性基础病,预防手术及介入性治疗后的感染,是减少败血症发生的重要措施,注意合理用药,细菌培养及药敏试验。
