卒中作为一个全球性健康问题,已成为全球范围内第二大常见死因,也是引起人类残疾最主要的原因.卒中多表现为突然发病、意识障碍、局灶性血流灌注和功能缺失.包括缺血性卒中和出血性卒中两种类型,具体临床表现有脑出血、蛛网膜下腔出血、脑动脉壁病变、脑组织缺血坏死等.
Coronary heart disease is a common disease threatening human health. In recent years, the incidence of coronary heart disease in China has only increased. It is the most common type of organ disease caused by coronary atherosclerosis, which is observed in the aorta, carotid artery, and femoral artery. The main clinical treatments for coronary heart disease include coronary artery bypass grafting and drug treatment. To investigate the relationship of serum adipocytokine C1q/tumor necrosis factor-related protein 9 (CTRP9), amyloid A (SAA), and plasma homocysteine (Hcy) with coronary artery plaque characteristics in patients with coronary heart disease. Overall, 143 patients with coronary heart disease admitted to our hospital are selected as research participants. The proportion of plaque necrosis core volume is higher in group A than in group B, and the differences are statistically significant (P < 0.05). In group A, necrotic core volume percentage is negatively correlated with CTRP9 levels and positively correlated with SAA and Hcy levels (P < 0.05). Logistic regression analysis revealed that increased systolic blood pressure, increased number of coronary artery lesions, decreased CTRP9 levels, and increased Hcy levels are independent risk factors for thin fibrous cap atherosclerosis in patients with coronary heart disease (P < 0.05). Decreased CTRP9 levels and increased Hcy levels are independent risk factors for coronary heart disease patients with thin fibrous cap atherosclerosis.
目的 分析低分子肝素对急性期非大面积心源性脑栓塞的临床治疗作用效果.方法 从我院患者中选择38例为研究对象,分为对照组和研究组,各19例,对照组患者使用乙酰水杨酸,研究组患者用低分子肝素,将两组患者的神经功能缺损程度分数、MBI分数进行对比.结果 两组患者在治疗之前的神经功能缺损程度分数与MBI分数(P>0.05)差异都无统计学意义,在治疗之后的6、12、18d,研究组患者的神经功能缺损程度分数会比对照组更低一些(P<0.05),MBI分数会明显的比对照组患者更高一些(P<0.05),两组患者之间的差异存在统计学意义.结论 低分子肝素对急性期非大面积心源性脑栓塞临床治疗效果明显有较大程度上的改善,适用于临床方面进行大量的推广和使用.
左心室室壁瘤（LVA）是指急性心肌梗死后,心脏局部室壁呈瘤样膨出于心室表面的病理改变[1],心室壁出现矛盾运动,致使心肌运动减弱或消失,从而产生心室射血分数降低的区域[2],其形成主要与局部心肌组织坏死、变薄,导致局部心肌收缩力减弱、心肌重构有关[3,4],可导致恶性室性心律失常、室间隔穿孔、心力衰竭、左心室附壁血栓等并发症,若出现心脏破裂死亡率达到100%[5,6]。LVA在急性心肌梗死存活患者中发生率为10%-38%[7],现将本院收治的1例急性心肌梗死并发巨大室壁瘤病例报道如下。
