目的:分析血清降钙素原与C-反应蛋白水平检测对患者早期感染的诊断价值.方法:选取我院2018年8月—2019年8月收治的174例感染性疾病住院患者作为观察对象,按其感染类型和程度划分为重度细菌感染组(39例)、一般细菌感染组(56例)和病毒感染组(79例).另选同期于我院体检的177例健康者作为对照组,所有对象均进行血清降钙素原和C-反应蛋白水平检测,对比检测结果.结果:重度细菌感染组与一般细菌感染组的血清降钙素原和C反应蛋白水平均高于对照组,差异显著有统计学意义(P<0.01);病毒感染组血清降钙素水平虽略有升高,但仍在正常范围内.与对照组比较无显著差异(P>0.05).结论:血清降钙素原与C-反应蛋白水平检测对感染性疾病有早期诊断意义,不过,病毒感染疾病不会导致血清降钙素原结果异常,所以在临床诊断时需要综合两者进行考量.

Objective To investigate the value of Serum cystatin C(CysC),urine albumin(mAlb),and β2-microglobulin(β2-MG) in the early diagnosis of diabetic nephropathy(DN).Methods 64 cases of patients with early DN (DN group),68 diabetic patients without nephropathy (NDN group),and 55 healthy volunteers (control group) in our hospital from January 2013 to December 2014 were selected as study subject.The serum CysC,β2-MG and morning urine mAlb levels of three groups were detected by immunonephelometry,and the energy efficiency of three indexes in DN diagnosis were analyzed.Results The serum CysC,β2-MG and morning urine mAlb levels of DN group were significantly higher than NDN group and control group (P<0.05).The positive rate of serum CysC,β2-MG and morning urine mAlb levels of DN group were 81.3%,53.1% and 76.6%,respectively,which were significantly higher than the positive rate of NDN group (1.5%,2.9%,and 4.4%) (P<0.05).The specificity of serum CysC,β2-MG and morning urine mAlb levels of DN group were 81.3%,53.1%,76.6%.The area under the ROC curve of CysC,β2-MG and morning urine mAlb in DN diagnostic were 0.899,0.751,and 0.861.The diagnostic efficiency of serum CysC was highest.Conclusion The detection of CysC,β2-MG,and morning urine mAlb could be used to DN early diagnosis.The sensitivity,specificity and efficient diagnosis of serum CysC were the best.

细菌耐药性是抗感染治疗中普遍存在的问题.为了解苛养菌感染及其耐药性,我们对医院1998年1月至2001年1月从感染性病人分离的肺炎链球菌﹑淋病奈瑟菌﹑流感嗜血杆菌的耐药性进行调查.结果报告如下.

随着自动化仪器在医学检验领域的广泛应用,检验结果的准确度和精密度有所提高,相关性分析更真实、可靠.本文应用自动化仪器测定了我院67例腰椎间盘突出症患者手术前后C反应蛋白(CRP)、血沉(ESR)和白细胞计数(WBC),并对该三项指标在手术前后的变化进行分析.现将结果报告如下.

临床工作中,常遇到病原菌感染的患者常规抗生素治疗效果不佳,需做病原学检测.而病人用了抗生素后采集的标本,用常规培养细菌的方法很难培养出病原菌,我科多年来共遇到31例用抗生素之后进行细菌培养而采集的标本.我们总结出两种方法,现报告如下.

临床工作中,偶尔遇到对病原菌感染的患者,常规抗生素治疗效果不佳,需做病原学检测,而患者用了抗生素之后采集的标本,用常规量培养细菌方法很难培养出病原菌,据统计,我科十多年来共遇到用了抗生素之后而采集标本,进行细菌培养的病例31例,经多年临床经验,我们总结出两种方法,用此方法18例标本培养出了致病菌,阳性率达到58%,方法如下.