患者男,41岁,无吸烟史.于2011年12月29日因咳嗽半年加重1个月入院,行CT检查示,左肺门占位,考虑肺癌;纵隔多发肿大淋巴结;少量心包积液;肝胃间多发淋巴结肿大.支气管镜检病理显示,左肺低分化癌,倾向腺癌.全身骨扫描示,全身多发骨转移.2012年1月6日开始给予吉西他滨1.8g,第1、8天;顺铂30 mg,第1、2、3、4天化疗及唑来膦酸抗骨转移治疗.化疗期间患者出现3～4度消化道反应.2个周期化疗后,患者出现左眼视野缺损,伴视物模糊.2012年2月11日经河南省人民医院眼科会诊.视力:右眼0.8,左眼0.4;眼底检查示,左眼底鼻上方局限性淡蓝色隆起伴有新生血管;眼底照相示,左眼眼底结节,性质待定.为明确诊断,进一步行MRI及眼球超声检查.MRI检查示,双侧眼球对称,左眼球后壁可见两处局限性增厚区.眼球超声检查示,左眼球壁扁平实性隆起,厚约3.05 mm,内呈中等回声,均匀,提示左眼球后壁实性占位.眼科会诊考虑恶性肿瘤眼部转移.复查CT示,左肺门肿块较前略缩小,多发骨质破坏范围较前略增大.遂换用厄洛替尼口服治疗.厄洛替尼治疗1个月后视力:右眼0.8,左眼0.6;左眼视野缺损消失.复查胸部CT示,左肺门肿块及纵隔淋巴结较前明显缩小.

Optical coherence tomography is a new type of medical imaging technology based on optical coherence characteristics in nearly twenty years.Since it need not contact with eyes when getting images,OCT has unique value in diagnosis of ocular trauma and examination before ophthalmic surgery.With an expression of pseudo color image and grayscale image,it can intuitively manifest anterior ocular segment (cornea,anterior chamber and anterior chamber angle,iris,ciliary body,lens,etc),retina and choroid,with information of shape,thickness and structure.This technology has many advantages,such as simply and fast operating,good repeatability,reliable data,high resolution,safe and noninvasive,etc.OCT has great application value in ophthalmic clinical work.This article will give a general review of the normal images,application in diagnosis of ocular trauma and ophthalmic diseases,and the late development of OCT.