输血相关性移植物抗宿主病(TA-GVHD)是输入含有免疫活性的淋巴细胞(主要是T 淋巴细胞)的血液和血液成分后发生的一种少见的致命性输血并发症,常见于免疫功能低下的病人[1 ] .该病临床表现类似于骨髓移植后移植物抗宿主病,如发热、皮疹、黄疸、呕吐、腹泻等,主要累及皮肤、胃肠道、肝脏[2] .研究显示,TA-GVHD 发病率为0 .01％ ～ 0 .10％ ,病死率为84％ ～ 100％ [3 ] .2016 年7 月我科成功救治1 例TA-GVHD 病人,现将护理报告如下.

Objective To investigate the effects of peer education on mouth－opening training compliance among patients with nasopha?ryngeal carcinoma after radiotherapy.Methods A total of 239 patients with nasopharyngeal carcinoma undergoing radiotherapy were divided into two groups.The control group (n＝121) was given routine care,and the experimental group(n＝118) received peer education.The inter?vention was provided from a week before radiotherapy to six months after radiotherapy.Results All patients completed radiotherapy.The ex?perimental group had lower incidence of difficulty in mouth－opening than the control group,and had higher mouth－opening training compliance compared with control group at the end of radiotherapy,3 months and 6 months after radiotherapy (P＜0.01 or P＜0.05).Conclusion Peer edu?cation can effectively improve mouth－opening training compliance in patients with nasopharyngeal carcinoma after radiotherapy,and decrease the incidence of difficulty in mouth－opening.

Objective To explore the effects of mindfulness-based intervention model on the quality of life and psychological status of lung cancer patients during chemotherapy.Methods A total of 76 patients with lung cancer during chemotherapy were randomly divided into control group and observation group,the control group were given routine nursing.In addition,patients in observation group received mindfulness-based intervention.The EORTC QLQ-30 and SAS scales,SDS scales were used to evaluate the quality of life of the patients before and after the 8-week intervention.Results Before intervention,there was no significant difference in quality of life (QOL) between the two groups.After 8 weeks of intervention,the overall health score of observation group was 59.6± 5.0,the control group was 59.6 ± 5.0.In fatigue,pain,nausea and vomiting,the score of observation was 43.2±2.7,26.2±4.3,30.5±5.6,and the control group was 57.8±4.2,47.8±3.9,51.4±5.6,the difference was statistically significant,the QOL of the observation group was better than control group,P＜0.05.Two groups of patients with anxiety,depression scores were reduced.The SAS score of observation group was 38.64 ± 5.02,the control group was 44.06± 5.24.And the SDS score of observation group was 41.26 ± 5.2,the control group was 46.89 ± 5.34,the psychologic status of observation group was better than the control group,P＜0.05.Conclusions Mindfulness-based intervention can effectively improve the psychological status and quality of life of lung cancer patients during chemotherapy.

目的 探讨微信平台在癌痛出院患者中的应用效果.方法 将240例中重度癌痛患者随机分为实验组和对照组各120例.出院后,对照组每周给予常规电话随访,实验组由研究者借助微信平台进行延续性护理.干预时间为3周.结果 干预后,实验组疼痛知识掌握、镇痛效果、服药依从性、生活质量、心理状态及满意度均优于对照组.结论 运用微信对癌痛出院患者进行延续性护理效果较好,值得推广.