消化性溃疡出血是临床常见病、多发病,以往患者多需采用手术治疗,导致患者痛苦,对生存质量影响较大,且需承担较高的医疗费用[1].随着临床消化内镜技术及相关器械的发展,多数患者可通过急诊内镜下进行止血,止血效果较为满意[2].临床有多种内镜止血方法,如病灶下止血、热凝、喷洒止血药、药物注射等均获得较为满意的止血效果,但临床对于直径>1.0 cm的溃疡灶处理较为困难[3,4].鉴于此,本研究旨在探讨大的消化性溃疡出血患者采用单钳道内镜下止血夹联合尼龙绳套扎环荷包缝合技术的临床效果,现报告如下.
目的:探讨奥曲肽联合奥美拉唑治疗急性上消化道出血的止血效果及安全性.方法:选择2018年4月-2019年4月我院收治的急性上消化道出血患者88例,采用随机数表法分为两组,各44例.对照组采用奥美拉唑治疗,试验组行奥曲肽联合奥美拉唑治疗.比较两组止血效果、治疗情况及治疗安全性,并统计再出血情况.结果:试验组止血有效率为95.45%(42/44),高于对照组的79.55%(35/44),差异有统计学意义(P<0.05);试验组治疗后止血时间、输血量及住院时间为(26.90±4.73)h、(144.81±19.92) mL和(7.88±1.65)d,均少于对照组的(38.74±6.65)h、(179.64±25.06)mL和(12.02±2.04)d,差异有统计学意义(P<0.05);试验组治疗后红细胞计数及血红蛋白含量为(3.48±0.47)×1012/L和(69.93±5.71)g/L,均分别高于对照组的(3.15±0.38)×1012/L和(65.78±4.63) g/L,差异有统计学意义(P<0.05);试验组不良反应总发生率为9.09%(4/44),与对照组的6.82%(3/44)相比,差异无统计学意义(P>0.05);试验组再出血率为4.55%(2/44),低于对照组的18.18%(8/44),差异有统计学意义(P<0.05).结论:奥曲肽联合奥美拉唑治疗急性上消化道出血效果显著,具有良好的止血效果及较高的安全性,且可改善血常规,利于尽早恢复.
Objective To investigate the effects of a stroke rehabilitation unit in stroke patients,and provide a theoretical basis for clinical treatment and care of stroke patients. Methods 90 cases of patients with stroke in our hospital from April 2012 to April 2013 were selected as the observation group,received stroke unit management,though 90 cases of stroke patients in our hospital from April 2011 to March 2012 were selected as a control group,received conventional management,the two management models on the rehabilitation of stroke patients were compared. Results The incidence of complications, treatment satisfaction rates in the control group were 26.7%,75.6% respectively;the incidence of disability,complications, treatment satisfaction rate in patients in the observation group was 4.4%,97.8%respectively,compared with the control group,the incidence of disability and complication rate were significantly reduced,treating satisfaction rate was improved significantly(P<0.05). Conclusion The stroke unit can significantly reduce the incidence of disability in stroke patients and the incidence of complications,and can significantly improve patient satisfaction, improve neurological function in patients,for the rehabilitation of patients with a significant role in promoting.