?AIM: To compare the visual quality in patients after implantation of extended - range - of - vision ( Tecnis Symfony ) intraocular lens ( IOL ) and zonal refractive ( Lentis Comfort LS-313 MF15) IOL.?METHODS: A prospective clinical study. Collecting 267 cataract patients ( 305 eyes ) who underwent phacoemulsification combined with IOL implantation surgery in our hospital from January 2021 to December 2021,they were divided into the Symfony group( group A, 160 eyes) and MF15 group ( group B, 145 eyes) according to the types of implanted IOL. Postoperative visual acuity were observed at 3mo and included uncorrected distance visual acuity ( UDVA, 5m ) , uncorrected intermediate visual acuity ( UIVA, 80 cm ) , uncorrected near visual acuity ( UNVA, 40cm ) , defocus curve, modulation transfer function ( MTF ) and high - order aberrations ( HOAs) , including coma, spherical aberration and trefoil aberration, and conducted the Quality of Vision ( QoV ) questionnaire.?RESULTS: There were no significant differences in the preoperative parameters in both groups (P>0.05). There was no significant difference between the UDVA and UNVA in groups A and B ( P>0.05);The UIVA was higher in group A than in group B ( P<0.05); The MTF value in group A was higher than group B at all spatial frequency, and the difference was statistical significant ( P<0.05);The HOAs in group A was lower than that in group B ( P<0.05 ); Defocus curves were plotted 3mo after the operation suggest that the visual acuity of the two groups was similar at 0D, and the visual acuity of the groups A was better than group B from -0. 5D to -2.5D, and there was a statistically significant difference at-1.0D and-2.0D ( P<0. 05 ) . The QoV score in group A was significantly higher than that in group B ( P<0. 05 ) . The frequency of bad visuaI interference such as halo and starburst was higher in group A than in group B.?CONCLUSION:Both the MF15 and Symfony can provide stable distance and near visual acuity. Compared with MF15, Symfony had better intermediate visual acuity, higher contrast sensitivity and lower HOAs. Compared with Symfony, MF15 IOL had less postoperative bad visual interference symptoms ( halo, starburst, etc) .

白内障术后人工晶状体(IOL)在眼内长期存在,可能会受眼球内部侵袭因素的影响,发生材料的老化或变性,影响IOL的成像特性,从而降低舒适度或影响视觉质量.目前被人们广泛关注且最具争论的材料退化形式是IOL的闪辉(glistening)现象.闪辉现象是IOL内部形成了充满液体的微泡.这些随机分布在IOL内部的液泡和IOL生物材料折射率的差异,会导致眼内的光散射增加.有研究报道严重IOL闪辉的患者会出现对比敏感度(CS)和调制传递函数(MTF)下降,影响视觉性能.本文就IOL闪辉现象对视觉质量的影响进行综述,并探讨闪辉的发生机制,以期人们对IOL闪辉现象有更深刻的认识,同时为IOL制造工艺的改进提供参考依据.