A spectrometer based on silicon nanosandwiches has been proposed to detect complications caused by COVID-19. Operating in the mode of a balanced photodetector, the silicon nanosandwich is both a source of terahertz irradiation and a receiver of reflected and/or radiated from biological tissue. It has been demonstrated that recording the current-voltage characteristics of a silicon nanosandwich made it possible to analyze changes in the thyroid gland, thereby determining the degree and nature of changes caused by the COVID-19 disease.. Keywords: silicon nanosandwich, terahertz irradiation, current-voltage characteristic, COVID-19.

A spectrometer based on silicon nanosandwiches has been proposed to detect complications caused by COVID-19. Operating in the mode of a balanced photodetector, the silicon nanosandwich is both a source of terahertz irradiation and a receiver of reflected and/or radiated from biological tissue. It has been demonstrated that recording the current-voltage characteristics of a silicon nanosandwich made it possible to analyze changes in the thyroid gland, thereby determining the degree and nature of changes caused by the COVID-19 disease.

The characteristics of terahertz (THz) irradiation generated by a silicon nanosandwich structure under the conditions of a stabilized drain-source current are demonstrated. The frequency of irradiation arising from the quantum Faraday effect is determined by the parameters of microcavities embedded in the edge channels of a silicon nanosandwich structure confined by the negative-U centers. The obtained characteristics of a compact THz irradiation source determine the basis for highly effective medical applications.

A spectrometer based on silicon nanosandwiches (SNSs) is proposed for problems of personalized medicine. SNS structures exhibit properties of terahertz (THz) emitter and receiver of the THz response of biological tissue. Measurements of the I–V characteristics of the SNS structure make it possible to analyze the spectral composition of the THz response of biological tissue and determine relative contributions of various proteins and amino acids contained in the structure of DNA oligonucleotides and the corresponding compounds. Evident advantages of the proposed method are related to the fact that the THz response can be directly obtained from living biological tissue and, hence, used for express analysis of the DNA oligonucleotides. Tests of several control groups show that the further analysis of the specific features of the spectral peaks of the SNS I–V characteristics is of interest for methods of personalized diagnostics and treatment.

A spectrometer based on silicon nanosandwiches (SNS) is proposed for solving problems of personalized medicine. Silicon nanosandwich (SNS) structures combine the properties of a terahertz (THz) emitter and a recorder of THz response from biological tissue. It has been demonstrated that recording the current-voltage characteristics (CVC) of the SNS structure allows us to analyze the spectral composition of the THz response from biological tissue and thus determine the relative contribution of various proteins and amino acids that make up the DNA oligonucleotides and their compounds. At the same time, the obvious advantages of the proposed technique are visible, since the THz response can be detected directly from living biological tissue, which can form the basis for the rapid analysis of DNA oligonucleotides. Further study of the behavior of the spectral peaks of the SNS C – V characteristics is of great interest for methods of personalized diagnosis and treatment, as demonstrated by the example of testing various control groups of subjects.

Abstract Here we present the first findings on the resonance response of DNA oligonucleotides deposited on silicon nanosandwich (SNS) and living bio-tissue to the THz irradiation that allow their identification by measuring the change of the longitudinal conductance and the lateral voltage within frameworks of the SNS prepared in the Hall geometry. The THz resonance response from living bio-tissue under the THz radiation is also applied to the definition of oncological diseases. The results obtained from the basis of the express diagnostics in practical medicine.

We present a method for the measurements of the tetrahertz (THz) resonance response of DNA oligonucleotides deposited on a silicon nanosandwich (SNS). It is shown that the SNS device can be used to generate a THz resonance response within living biotissue. The technique we propose measures changes of the longitudinal conductance and the lateral voltage with the SNS device in a Hall geometry. The mechanism of the THz response is discussed, with a model of the generation of Shapiro steps. The THz resonance response from living biotissues will aid the diagnosis of oncological disease and, in general, form the basis of a rapid diagnosis in practical medicine.

We demonstrate a novel approach to the problem of express diagnostics based on THz spectral features of the breast cancer and THz emission and detection provided by the topological edge channels of silicon nanosandwichstructures.

The negative-U impurity stripes confining the edge channels of semiconductor quantum wells are shown to allow the effective cooling inside in the process of the spin-dependent transport, with the reduction of the electron-electron interaction. The aforesaid promotes also the creation of composite bosons and fermions by the capture of single magnetic flux quanta on the edge channels under the conditions of low sheet density of carriers, thus opening new opportunities for the registration of the high temperature de Haas-van Alphen, 300 K, quantum Hall, 77 K, effects as well as quantum conductance staircase in the silicon sandwich structure.