Objective To investigate the expression of Caveolin-1 and RhoE in primary liver carcinoma (PLC),and their relation to the clinicopathological features and the prognostic value.Methods Immunohistochemical method was used to assess the expression of Caveolin-1 and RhoE in 20 normal liver tissues,32 cirrhosis tissues and 68 PLC tissues.Results The expression rate of Caveolin-1 in normal liver tissues,cirrhosis tissues and PLC tissues was 85.00% (17/20),56.25% (18/32) and 27.94% (19/68) with significant difference (P < 0.05).The expression levels of Caveolin-1 were related to histology grade and blood vessel invasion of PLC (P < 0.05).The expression rate of RhoE in normal liver tissues,cirrhosis tissues and PLC tissues was 95.00% (19/20),71.88% (23/32) and 50.00% (34/68) with significant difference (P < 0.05).There was a close relation between the expression of RhoE and histology grade,blood vessel invasion and TNM stage (P < 0.05).Conclusion The expression of Caveolin-1 and RhoE may play an important role in the carcinogenesis of liver carcinoma.
目的:探讨右半结肠癌误诊为急性阑尾炎的原因.方法:回顾性分析大庆龙南医院2003-03/2009-10收治的右半结肠癌误诊为急性阑尾炎18例的临床资料.结果:术后恢复良好,无死亡病例.术后并发局限性腹膜感染1例,经保守治疗治愈;并发切口感染2例,经换药愈合.结论:早期结肠癌患者症状不典型,详细的病史询问及体格检查和术中仔细探查是避免结肠癌误诊、漏诊的有效措施.