OBJECTIVE To explore the clinical characteristics and prognosis of the liver cirrhosis patients complicat‐ed with septic shock so as to provide guidance for early prevention and control of septic shock in the liver cirrhosis patients and improve the survival rate .METHODS Totally 527 liver cirrhosis patients who were treated from Jan 2013 to Dec 2013 were enrolled in the study ,and the clinical data of 86 participants complicated with septic shock were retrospectively analyzed ;the clinical characteristics and prognosis of the liver cirrhosis patients complicated with septic shock were observed ,and the coping strategies were put forward .RESULTS The septic shock occurred in 86 of 527 liver cirrhosis patients ,with the incidence rate of 16 .32% ;totally 10 of 441 patients without septic shock died ,with the mortality rate of 2 .27% ;while 9 of 86 patients with septic shock died ,with the mortality rate of 10 .47% .Of 86 liver cirrhosis patients complicated with septic shock ,38 (44 .19% ) had pulmonary infec‐tions ,and 27 (31 .39% ) had abdominal and intestinal infections .A total of 75 strains of pathogens have been iso‐lated from the submitted specimens ,including 41 (54 .67% ) strains of gram‐negative bacilli ,14 (18 .67% ) strains of gram‐positive cocci ,and 20 (26 .66% ) strains of fungi .The risk factors for septic shock in the liver cirrhosis patients included the age ,serum albumin ,prophylactic use of antibiotics ,gastrointestinal hemorrhage ,hepatic en‐cephalopathy ,and length of hospital stay .CONCLUSION It is of great significance to take the coping strategies ai‐ming at the risk factors based on the clinical characteristics of the liver cirrhosis patients complicated with septic shock so as to reduce the incidence of septic shock and improve the prognosis .

目的调查余姚地区儿童变态反应性疾病外过敏原分布情况,为疾病防治提供科学依据。方法对608例变态反应性疾病患儿行皮肤点刺,进行外过敏原筛查;按年龄分为≤7岁组和7～12岁组两组进行过敏原阳性率观察。结果 608例儿童阳性率为69.74%。其中≤7岁组阳性率56.90%,7～12岁组阳性率87.69%。螨虫阳性率≤7岁组为55.17%,7～12岁组为86.15%。结论儿童变态反应性疾病过敏原以螨虫和动物皮毛为主。

细菌性痢疾是夏季常见的肠道传染病,志贺菌是引起细菌性痢疾的主要病原菌[1].由于抗菌药物的广泛应用,志贺菌的耐药性不断增加,甚至呈多重耐药[2-3].为了解本地区志贺菌的流行及耐药情况,笔者对45株福氏志贺菌和19株宋内志贺菌进行耐药性检测,以期对临床合理用药提供依据.

细菌性痢疾是志贺氏菌属引起的肠道传染病,了解志贺氏菌属群间的分布及抗药变化,对菌痢的流行病学分析,预防和临床治疗都具有指导意义.我们对1998-05～2002-07从门诊和住院患者中分离出106株福氏志贺氏菌进行耐药性分析,现将结果报告如下.