In this report, chest drain wound closure using barbed suture material in patients with thoracic disease is presented. From October to December 2019, 77 patients underwent thoracic surgery and closed chest drain wound using barbed suture material. Of them,（ median age 67 years, range 16 to 89 years） 51 were men （66％） and 26 were women. Most was 50 cases of primary lung cancer （65％）. Chest tube was inserted after continuous subcutaneous suture by barbed suture material. The mean chest tube duration was 2.3±0.6. No harmful events due to this procedure nor wound complication during the median follow-up period of 1 months after operation were noted.