脊柱念珠菌感染在临床上较少见,由于其临床表现、实验室检查、影像学检查表现缺乏特异性,诊断较困难,尽早进行活检获取组织进行培养是诊断的金标准。脊柱念珠菌感染的抗真菌疗程较长,部分患者需联合手术治疗。本文回顾性分析2019年1月至2021年8月浙江大学医学院附属邵逸夫医院确诊的4例脊柱念珠菌感染患者的病例资料,并结合文献进行讨论分析。
The clinical and magnetic resonance imaging(MRI) data of 8 cases of fungal spondylitis were retrospectively enrolled in the study, and the typical MRI findings were mainly discussed. The results released that fungal spondylitis should be suspected when the infection spreads along paraspinal ligament, and vertebral lesions show jumping discontinuous distribution. A blurred and incomplete outline of endplate on T1 weighted imaging sequence, loss of hyperintensity of the vertebral body, and banded like hypointensity under endplate on T2 weighted imaging sequence, indicate fungal spondylitis. These features contribute to the diagnosis and differential diagnosis of fungal spondylitis.