Introduction. Genitourinary syndrome of menopause (GSM) is a complex of symptoms resulting from changes to the vulvovaginal region, urethra and bladder due to estrogen and other sex steroid deficiency. Vulvovaginal atrophy is one of its manifestations, and vaginal dryness, dyspareunia, burning and itching are the most common symptoms.Aim. To analyse 20 clinical cases of the use of innovative laser procedures combined with phytoestrogens in patients with vulvovaginal atrophy as a symptom of GSM vs the standard systemic protocol for menopausal hormone therapy.Materials and methods. A clinical case-control study was conducted among 20 postmenopausal women. The age of the subjects ranged from 50 to 65 years with amenorrhea for at least 1 year, a follicle-stimulating hormone level of >30 IU/L and various presentations of GSM. The women were divided into two groups: group 1 (n = 10) received laser therapy combined with phytoestrogens, group 2 (n = 10) received systemic menopausal hormonal therapy. To evaluate the results, a survey with a specialized international vulvovaginal symptom questionnaire (VSQ) was carried out to determine the vaginal health index scores before and after treatment.Results. After treatment, both groups showed significant improvement in the form of the reduction or disappearance of symptoms of vulvovaginal atrophy. The prescription of phytoestrogens provided an additional positive effect after 3 sessions of carbon dioxide laser treatment.Conclusion. The carbon dioxide laser exposure resulted in the reduction or disappearance of the local symptoms of climacteric syndrome in the form of GSM, and the use of phytoestrogens as part of Mense BAA supplemented the treatment of psychoemotional and neurovegetative changes, which allowed us to make a conclusion about the feasibility, high efficiency and safety of the complex treatment for women, who do not wish to take menopausal hormone therapy and (or) have absolute contraindications. However, further research on the laser technologies and other non-hormonal techniques to treat GSM is required to carry out a more complete and accurate assessment of the effectiveness and safety of these treatments.
Data are presented on the stages of aging of the female reproductive system and the symptoms developing in these age periods. It is noted that the pathogenesis of development of urogenital disorders are connected with decrease in the level of estrogens in the peri- and postmenorausal period. Effective therapy for women with vaginal atrophy is the administration of estriol preparations (Оvestin) in the form of a cream or vaginal suppositories.
This article is devoted to the review of domestic and foreign data on the efficacy and safety of non-invasive erbium laser therapy aimed at increasing the tone of the pelvic floor muscles. The search for literature data allowed to reveal a lot of studies describing the successful experience of non-invasive laser procedures in gynecology, as well as not only the high effectiveness of the method, but also its safety. This type of therapy represents a promising treatment technology with a high level of efficacy and an optimal safety profile.
This article describes the present views on ultrasound diagnosis of infertility. The generalized data on modern techniques. Pressing questions of the most common causes of infertility.
This article describes the present views on the treatment of genital herpes infection. Examined topical therapies HSV.
This article describes the present views on ultrasound diagnosis of cervical changes. The generalized data on the size and measurement procedures. Pressing questions of the most common changes in the cervix.
The goal of anti-aging menopausal hormone therapy (MHT) lies in maintenance and restoration of the major organs and body systems, thus achieving two main effects: increasing life expectancy and improving its quality, which is fully consistent with the desires of women in perimenopausal and postmenopausal women. MHT started in the menopausal transition period is not only the treatment of early symptoms of menopause, but menopause itself and prevention of late complications. The article discusses the possibility and efficacy of Angeliq® Micro containing reduced doses of estrogen and progestogen (17β-estradiol 0.5 mg + drospirenone 0.25 mg). Indications for its purpose is to maintain moderate to severe hot flashes in postmenopausal women with an intact uterus.
The article tells about the occurrence and course of surgical menopause in women of reproductive age. Management principles for this group of patients and options for hormone therapy, in particular estriol monotherapy, are discussed.
This article describes the present views on ultrasound diagnosis of cervical changes. The generalized data on the size and measurement procedures. Pressing questions of the most common changes in the cervix.
This article describes the present views on ultrasound diagnosis of infertility. The generalized data on modern techniques. Pressing questions of the most common causes of infertility.