For successful treatment of patients with chronic and complicated forms of different organs and systems' epithelial plates' damages the epithelial layer's immunological properties study is of current interest. The investigation showed that the IL-8 content in patients is two times as less than that in healthy persons. One of the mechanisms of local phagocytic protection insufficiency one can explain by the disfunction of proinflammatory interleukins-1 (IL-1a, IL8), owing to these inflammatory mediators' activity fall-off, that clinically is manifested by a chronic run of the infection process and conditions the inefficiency of causal treatment.