We have synthesized a series of 1,3-dimethyl-6-(5'-aminopyrimidyl-6-thio)uracyl derivatives, studied their conversions, and characterized some of their properties.

In continuation of the search for new biologically active compounds among bi- and tricyclic systems of 1,4-thiazine and 1,4-thiazepine, we have synthesized derivatives of the previously unreported heterocyclic system of dipyrimido[4,5-b][5,4-f]-1,4-thiazepine.

Derivatives of 1,3-dimethyl-6-(5′-aminopyrimidylthio-6′)uracils were synthesized and some of their properties and reactions were studied.

Derivatives of dipyrimido[4,5-b][5,4-f]-1,4-thiazepine were synthesized and some of their properties were studied.

We have studied some properties and conversions of pyrimido[4,5-b]-1,4-benzothiazepines: reduction, oxidation, reactions with nucleophilic reagents (methanol, hydrazine, hydroxylamine, o-methylhydroxylamine, and thiosemicarbazide). We have synthesized derivatives of a novel heterocyclic system: pyrimido[5,4-c]isoquinoline.

AbstractFor Abstract see ChemInform Abstract in Full Text.

A series of pyrimidyl aryl sulfides was obtained from the reaction of 5-amino-6-mercaptopyrimidines with derivatives of p-chloronitrobenzene containing carbonyl functional groups. The properties of these sulfides and methods of their cyclization into derivatives of a new tricylic system, pyrimido[4,5-b]-1,4-benzothiazepine, were studied.

The reaction of o-haloamino derivatives of pyrimidine and pyridine with o-hydroxy-benzaldehyde and its derivatives leads to the formation of tricyclic 1,4-oxazepine systems. Syntheses are reported for derivatives of pyrimido[4,5-b]- and pyrido[2, 3-b]-1,4-benzoxazepines as well as of their 5,6-dihydro derivatives. The properties and structures of these compounds were studied.

Abstracto‐Phenylendiamine (I) und (IV) reagieren mit Diketonen (II) zu Diazepinen (III) bzw. (V), die in Form ihrer Salze mit Salzsäure, Perchlorsäure, Oxalsäure, Citronensäure und Pikrinsäure isoliert werden.