In the literature there is little information about the occurrence of dielectrolytes with inadequately selected parenteral-enteral correction. This fully applies to the correction of iron deficiency in colorectal cancer (CRC). Material and methods. On examination were 51 patients with CRC (T3N1M0 and T4N0M1) and iron deficiency of various severity. Nutritional status was assessed by the parameters of a known alimentary-volemic diagnosis (AED). Iron deficiencies resulting from chronic blood loss were assessed by the content of serum iron, ferritin, transferrin, the level of Hb and Ht, the number and average volume of red blood cells, and the average content of Hb in the red blood cell. The control group consisted of 10 patients with iron-deficient anemia. Results. One of the components of the AVD is the determination of electrolyte deficiencies, including gland. With a deficit of free iron in plasma up to 11%, a decrease in hemoglobin level and Ht, a slight decrease in the number of erythrocytes and normal parameters of ferritin, the average volume of erythrocyte and the content of Hb in it were sufficient nutritive correction mixtures containing 3.0-3.5 mg of iron in 100 g dry product. With a higher iron deficiency, additional parenteral administration of its drugs was required: as part of the nutritional correction, as a pharmacological supplement, supplements were injected with non-sorbed or sorbed iron on a special matrix (ironMatrix), which guaranteed the stability of the iron complex and its controlled release in the body. At the same time, sorbed iron provided a higher safety (no complications were observed in any of the studies. with the administration of non-sorbed iron in 2 cases, there were unpleasant sensations in the heart area, in the right hypochondrium, resembling signs of iron overload (ferritin could increase to 1340 mg), stopped, however, only by the administration of a hepatoprotector and 0.9% of the sodium chloride solution without the additional use of an antidote. Conclusion. For the sake of safety of iron deficiency correction (prevention of toxic-metabolic complications) when conducting a comprehensive nutritional correction in patients with CRC complicated by mild chronic anemia with iron deficiency not more than 11%, it is advisable to use drugs containing iron (3-3.5 mg per 100 g of dry product), and in case of a pronounced shortage of it, supplement the nutritional support with parenteral preparations of sorbed iron under the control of the parameters of iron metabolism.

Six patients with right-sided hemihepatectomy were observed. In the preoperative period, along with clinical and laboratory, CT, ultrasound, gastroscopy, the functional reserve of the liver was assessed before and after the operative increase in the volume of the left lobe of the liver. We estimated not only the increase in volume, but also the functional preservation of liver functions. The criterion of nutritional consistency was the well-known alimentary-vollemic diagnosis. Given the high nutritional risk, a nutritional correction included a mixed nutrition (sparing diet + sipping with a mixture of hepatoprotective composition, enzyme therapy and parenteral correction with electrolyte solutions, vitamins and albumin). Against the background of the correction, the patient’s state was satisfactory with positive dynamics.

The article describes the modern data on the prevalence of ulcerative colitis, presents data on the factors of pathogenesis, main tasks, directions and scheme of nutritional support depending on the activity of the disease, nutritional deficiency and immune status of the patient.

The aim is to develop recommendations for the use of nutritional schemes for palliative care for cancer patients. Material and methods. The severity of the condition, the degree of protein-energy deficiency and organ deficiency (according to the method of alimentary-vollemic diagnosis), the degree of nutritional risk, the stage of the process, the assessment of the intensity of intoxication, the state of the immune system and genomic prognosis were assessed in cancer patients. Criteria for assessment of homeostasis in all patients with oncopathology are divided into 3 main groups: 1) patients who could performed radical surgery and/or comprehensive treatment; 2) patients receiving at the time of providing support to various regimens; 3) patients requiring only palliative care. With this gradation, the use of information, literature data and own observations, we proposed for each group a specialized nutritional program. Results and discussion. Patients in need of palliative care were diagnosed with asthenia, early satiety, progressive weight loss, anorexia, tissue protein deficiency, the growth of pro-inflammatory cytokines and tumor-specific cachexia factors. For such patients, a program is proposed that includes a diet, sipping with the use of a caliper; In the case of probe alimentation, partially disintegrated formulations are recommended (for example, nutrihim). In severe patients, the nutritional effect was enhanced by progestogen preparations (megas, ondasetron), anti-catabolic agents (indomethacin, ibuprofen, EPA), anabolics (retabolil). Conclusions. The composition of the sipping rations should include nutrients that affect the molecular mechanisms of survival, apoptosis of tumor cells, proliferation, angiogenesis and invasion of tumor cells.

In article presented the theme of nutritional support in severe ulcerative colitis. A study was conducted which aimed at improving the nutritional support in ulcerative colitis and integration of schemes elaborated on the basis of pathogenesis into the structure of the treatment of ulcerative colitis. Examination of patients was performed in accordance with the standard of reference for the patient, starting with the collection of complaints, anamnesis of disease and life history of the patient. All patients underwent traditional laboratory tests, enzyme immunoassay was used to determine the concentration of IgG, IgM, IgA, intercellular adhesion molecules. Evaluation of activity of ulcerative colitis was performed according to a known scale Mayo (represented Rachmilewitz 1989), taking into account the frequency of bowel movements bleeding, endoscopic assessment of colonic and a General assessment of the condition of the patient. Nutritional status was evaluated according to the criteria known alimentation-volemic diagnosis. It is noted that the high activity of ulcerative colitis increases the level of C-reactive protein, the magnitude of which correlates with other immunological parameters. Considering the data obtained by choosing nutritional support used the compositions selected depending on the severity of immune disorders and the degree of nutritional deficiency. Conclusions: 1. If complications arise during the ulcerative colitis, leading to surgical treatment and requiring metabolic correction, assessment of nutritional risk can be considered as an additional criterion for permitting or restricting the indications for surgical treatment. 2. The severity of nutritional deficiency depends on the extent of injury, severity disease and activity of ulcerative colitis. 3. The functional reserve of the intestine is one of the main factors limiting the absorption of nutrients in severe and complicated ulcerative colitis. 4. Nutritional support in the treatment of complicated UC must include in preoperative preparation for urgent and planned interventions, as well as in the postoperative period. For nutritional environments preoperative preparation and additional nutritional rehabilitation should be considered as the degree of nutritional deficiency, and the activity of UC.

A lot of patients with short bowel syndrome should receive in nutritional support. It is necessary to develop algorithm of nutritional support being based on classification of extensive intestines resections. The new our classification will help doctors effectively treat patients with syndrome оf malabsorption.

Aim to study: The study of antimicrobial activity, hidrofobisity and physicochemical properties of nanostructured barrier layers on the surface of polyethyleneterephtalate and polytetrafluorethylene, formed by different methods of ion-plasma technique.

Aim to study: The study of antimicrobial activity, hidrofobisity and physicochemical properties of nanostructured barrier layers on the surface of polyethyleneterephtalate and polytetrafluorethylene, formed by different methods of ion-plasma technique.

Методы экспресс-диагностики нутритивной недостаточности – актуальное направление нутрициологии. Многие из них входят в структуру алиментационно-волемического диагноза (АВД). Одним из компонентов АВД является определение потребностей в белке, углеводах и липидах у каждого конкретного больного. Сравнение расчётных энергопотребностей с результатами полученных измерений с помощью метаболографа свидетельствует о целесообразности измерения именно этих данных. Измеренные параметры обладают рядом преимуществ: позволяют предотвратить ряд метаболических осложнений, обеспечивают экономический эффект, способствуют стимуляции дыхания. В статье также представлен клинический случай больного, находившегося в ОРИТ, у которого энергопотребности, определяемые по метаболографу, были существенно ниже по сравнению с расчётными данными, что потребовало коррекции нутриционной программы. Такая коррекция способствовала не только оптимизации обменных процессов, но и более рациональному расходу препаратов.

In the presented clinical case the theme of the need for an integrated therapeutic intervention has been disclosed, including nutritional support on the various links of the pathogenesis of esophagospasm to the effectiveness of the patient's treatment.

The article presents the data on the assessment of nutritional status, taking into account humoral immunologic criteria of patients with ulcerative colitis.

The article presents the data on the assessment of the degree of severity of ulcerative colitis and the selection of nutritional support with the account of the violations of the nutrition status with ulcerative colitis.

The article presents the data on the assessment of the degree of severity of ulcerative colitis and the selection of nutritional support with the account of the violations of the nutrition status with ulcerative colitis.

In the presented clinical case the theme of the need for an integrated therapeutic intervention has been disclosed, including nutritional support on the various links of the pathogenesis of esophagospasm to the effectiveness of the patient's treatment.

The aim of the research determine the character and peculiarities of nutritional support in surgical treatment of patients with gastroresection— and total gastrectomy syndromes. Analyzed are the results of the evaluation nourishing status of 68 patients who have had a resection intervention on the stomach. It was noted that the 26.5% of patients with clinical manifestations of diseases of operated stomach arise suband decompensated forms of disorders metabolism and nutrition, entailing numerous violations of homeostasis and requiring compliance with reconstructive surgical interventions. We studied the results of the implementation of the reconstructive operations with the formation of functionally active жомно-valve соустий in 18 patients, suffering from the disease of stomach operated on. It is proved, that the rational nutritional support in the perioperative period allows to avoid gross violations of metabolism and provides a reasonably good compensation digestive function, significantly improving the quality of life of this category of patients.

The article has revealed the relevance of nutriciology as a science, classification and types of nutritional support. Nutritional support diagnostics and the metabolic correction of arising violations of various kinds of homeostasis, aimed at ensuring the functioning of the systems of protein-energy synthesis and intermediate exchange of nutrients, vitamins, macro and microelements, or a temporary replacement therapy of their failure. The notions of «lack of food», «artificial» food, protein-energy insufficiency with the exception of the syndromes of malabsorption, alimentary anemia, the effects of protein-energy malnutrition, consumptive disease, starvation have been interpreted. It was noted that nutriciology has taken place as a science. The problems of prognostification of nutritional deficiency, assessment of nutritional risk, the organization of nutritional support in the hospital and at home have been presented. Some fundamental bases of enteral probe feeding have been described.