The article sums up long-term, researches of studying of species and genetic variety of tick infections pathogens in combined, natural focuses of the Eastern Siberia. The results of the research testify to the high genetic variety of regional population, of tick-borne encephalitis virus that is represented, by the strains of Far-Eastern, West, Ural-Siberian genotypes, the strains of the group 886 and. 178-79. Infection of Ixodidae by the next pathogens: B. garinii, B. afzelii, R. sibirica, R. raoultii (генотипы. R. sp. DnS14, R. sp. DnS28), E. muris, A. phagocytophilum и Candidatus «Neoehrlichia mikurensis» was determined.
Genotyping of nine strains and nine isolates of tick-borne encephalitis virus RNA (TBE) isolated from patients in the Irkutsk Region and. the Buryat Republic in 1963-2009 years conducted. The investigations revealed that three TBE virus genotypes are involved in the etiology of the TBE: Ural-Siberian (genotype 3), Far Eastern (genotype 1) and. European (genotype 2). It is found that the TBE virus of Far East and. Ural-Siberian genotypes can cause disease with a wide spectrum of clinical manifestations: acute TBE (focal and. nonlocal forms), chronic TBE (encephalitic form, progressive course.) Prospects of application of molecular genetic techniques for the rapid indication and. identification of the TBE virus in the blood of sick people are shown.