The influence of the structure-related physicochemical properties of derivatives of nitrogen-containing heterocyclic compounds on their retention under the conditions of reversed-phase liquid chromatography was studied. The dependence of the chromatographic retention of azole derivatives on the composition of the mobile phase was determined. The presence of azole protonated forms was substantiated by conductometric data.

Correlations between physicochemical properties and chromatographic retention parameters of adamantane derivatives were studied. The Kovats indices and contributions of hydrocarbon radicals and functional groups to the chromatographic retention were calculated from the experimental data.

The potential of the structural analogy method in the topological studies of adamantane derivatives and analogs is demonstrated. The topological and structural characteristics of these compounds are calculated. Chromatographic retention indices were determined experimentally. Correlations between the topological indices and the physicochemical and chromatographic characteristics are investigated.

Topological characteristics of alkyladamantanes are calculated. Correlations between Randiç indices and some physicochemical parameters of the structural analogs of adamantane are investigated.

Chromatographic characteristics of adamantyl silicone stationary phase were studied.