The thermal behavior of collagen in intact and IR laser irradiated nucleus pulpose tissues was studied. The enthalpy of denaturation of the intact tissue was determined (53.1 ± 1.2 J/g of collagen). The denaturation of collagen during laser heating at temperatures below the characteristic melting point occurred under the influence of the photomechanical component of laser irradiation.
The thermal stability of collagen in intervertebral disc tissues was studied using differential scanning calorimetry. It was found that the melting of collagen in a native tissue was complete at 62–75°C (ΔH = 62.4 J/g) under heating excised annulus fibrosus and nucleus pulposus samples. On heating an intact structure up to 80°C, the denaturation of collagen did not occur. It was shown that the degradation of a proteoglycan component in the test tissues had no effect on the thermal stability of collagen.
Olga Zakharkina合作论文数7
S. V. Averkiev合作论文数4н ю игнатьева合作论文数3Valery Lunin合作论文数Chemistry Department, Lomonosov Moscow State University3м в обрезкова合作论文数2
N. Yu. Ignat’eva合作论文数2
Emil N Sobol合作论文数Beckman Laser Institute, University of California, Irvine;Medical Clinic, University of California, Irvine;Arcuo Medical Inc2V. A. Kamenskii合作论文数2Ignat'eva N Iu合作论文数1
V. A. Kamensky合作论文数Institute of Applied Physics, the Russian Academy of Science1N. Yu. Ignatieva合作论文数1Alexey V. Myakov合作论文数1
