Introduction. In the Russian Federation there is a constantly updated register of infections associated with surgery and the treatment of oncological diseases reporting which is mandatory. Massive expenses and detriment to patients’ health caused by these infections prompted the authors to run a retrospective epidemiological analysis of the morbidity registered in the population of the city of Kazan during the period under review. This paper presents a study of patterns of the emergence and spread of nosocomial infections.This study aims to examine the clinical and epidemiological characteristics of infections associated with surgery and the treatment of oncological diseases registered in the population of the city of Kazan.Materials and methods. Authors analysed the Emergency Notifications for an Infectious Disease (form 058/u) as well as the data from the Rospotrebnadzor Federal Statistical Record Form №2. The paper presents the morbidity annual dynamics, structure and spatial characteristics and describes key pathogens of HAIs.Results and discussion. On the basis of the data obtained the authors give clinical and epidemiological characteristics of the annual dynamics of the morbidity characterised by recurrent rises during the year with the top incidence in the autumn. Neonatal PSI infections dominate the HAIs incidence structure (52.8%). St. aureus is the priority HAI pathogen (26.5% of cases) in the city of Kazan.Conclusion. Microbiological monitoring of emerging HAIs is an efficient tool for managerial decision making and the development of an algorithm for anti-epidemic measures in the departments and the hospital as a whole for the reduction of risk of infection.

The retrospective epidemiological study was carried out concerning infections related to medical care support registered in population on the territory of the Republic of Tatarstan in 2002-2015. The reason of such a study was because of late identification and registration of infections related to medical care support, significant damage to population health, development of complications in significant percentage of hospitalized patients and necessity of investigation of patterns of development and outspread of nosocomial infections. The epidemiological analysis was implemented using report form of the Federal statistical observation № 2 of the Federal service of control of sector of defense of rights of consumers and human well-being “The data of infectious and parasitic infections”. The dynamics, structure of many years morbidity and main parameters of manifestation of epidemic process were investigated. The derived data was used as a basis to provide epidemiological characteristic of many years' dynamics of various classes of infections related to medical care support. The indices of morbidity are calculated with consideration for average annual population size. The priority nosologic forms of infections related to medical care support were established concerning newborns (pyodermatitis, conjunctivitis, pneumonia, omphalitis, sepsis, etc.), puerpera (pyo-septic infections, mastitis, sepsis), adult population (postoperative and post-injection complications, infections of urinary tracts, nosocomial pneumonia, viral hepatitis, etc.) which dynamics was characterized by positive and negative rate of increment of indicator. The obtained data was compared with indices represented in national and foreign publications. The implemented study testifies the necessity of development of measures epidemiological monitoring of decreasing of morbidity because of infections related to medical care support in medical organizations.

The scientific approach to development of new preventive direction is substantiated concerning support of hygienic safety of industrial and environmental medium and protection and enhancement of health of working people. This approach is based on methodological support of implementation of healthand resource-preserving technology at enterprise of transport engineering industry. The evaluation is given concerning effectiveness of application of system of medical preventive activities and sanitary hygienic and industrial economic principles and philosophy of organization of “lean production” in management of risks for health of working people.